RECRUITING

Inspiring Seniors Toward Exercise Promotion to Prevent Alzheimer's Disease

Description

The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints. Specific Aims are to determine (1) whether BMS beneficially influences PA behaviors and psychological responses to PA in older adults for 6 months, and (2) whether exercising with BMS differently influences physical and cognitive functioning as well as quality of life in older adults.To test the effects of BMS on PA, participants will be randomly assigned to an exercise intervention that either includes BMS or does not include BMS. Participants will attend a supervised group strength training (ST) (30 min/day) and and aerobic exercise (AE) (30-50 min/day) session for 3 days/week for the first 2 months, 1 day/week for the next 2 months (while encouraging participants to independently perform both AE and ST on other days), and independently for the final 2 months (always with a goal of performing \>150min/week AE and 3 days/week of ST for 30 min/day).

Conditions

Alzheimer Disease
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Related Conditions:

Alzheimer Disease

Study Overview

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Study Details

Study overview

The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints. Specific Aims are to determine (1) whether BMS beneficially influences PA behaviors and psychological responses to PA in older adults for 6 months, and (2) whether exercising with BMS differently influences physical and cognitive functioning as well as quality of life in older adults.To test the effects of BMS on PA, participants will be randomly assigned to an exercise intervention that either includes BMS or does not include BMS. Participants will attend a supervised group strength training (ST) (30 min/day) and and aerobic exercise (AE) (30-50 min/day) session for 3 days/week for the first 2 months, 1 day/week for the next 2 months (while encouraging participants to independently perform both AE and ST on other days), and independently for the final 2 months (always with a goal of performing \>150min/week AE and 3 days/week of ST for 30 min/day).

Music Stimulation for Physical Activity of Older Adults at Risk of Dementia

Inspiring Seniors Toward Exercise Promotion to Prevent Alzheimer's Disease

Condition
Alzheimer Disease
Intervention / Treatment

-

Contacts and Locations

Greensboro

UNC Greensboro, Greensboro, North Carolina, United States, 27412

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adults at least 65 years old.
  • * Ambulatory/capable of walking for 6 minutes without pain or aid such as a walker/cane.
  • * Able to speak and read English.
  • * Healthy enough to exercise at moderate intensity with or without medical clearance by a primary care physician.
  • * Living in the community for the duration of the study (6 months).
  • * Having a reliable means of transportation.
  • * Having a safe place (at least 6 feet by 6 feet of open space) at home for unsupervised exercise training.
  • * Having self-perceived memory complaints.
  • * Having no symptoms of suicidal ideation and not meeting criteria for depressive disorder.
  • * Physically low-active by doing \< 60 min/week of moderate-intensity aerobic exercise and no strength training for the last 3 months.
  • * Diagnosis of neurological disorder or spinal cord disorder.
  • * Known exercise contraindications.
  • * Current cancer treatment.
  • * Stroke or neural impairment in the past 6 months.
  • * Hip/knee/spinal fracture or surgery in the past 6 month.
  • * Unable or unwilling to attend intervention classes 3x/week in Months 1-2 and 1x/week in Months 3-4.
  • * Currently participating in any other physical activity or fitness-related research study.
  • * Use of medication for Alzheimer's disease. Change in dosage of medications prescribed for anxiety or depression within the previous 6 months.
  • * Regularly drink \> 14 alcoholic beverages a week or current illicit drug use.
  • * Meet the threshold for cognitive impairment.
  • * Meet the threshold for clinical depression.
  • * Uncorrected hearing or visual impairments.
  • * Unable to understand the study procedures.
  • * One of the household members is participating in this study.

Ages Eligible for Study

65 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of North Carolina, Greensboro,

Kyoung Shin Park, PhD, PRINCIPAL_INVESTIGATOR, University of North Carolina, Greensboro

Study Record Dates

2026-03