RECRUITING

Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this randomized placebo controlled trial is to examine mood disturbance and serum brain derived neurotrophic factor (BDNF) in people (age 18-50) with DASS-21 subscale scores \>9. The main questions it aims to answer are: Does curcumin and EGCG supplementation improve mood disturbance symptomology? Does curcumin and EGCG supplementation increase serum BDNF? Researchers will compare intervention versus placebo. Participants will consume an 8-week supplement of both: * 1,330mg/day curcumin * 350mg/day epigallocatechin gallate (EGCG)

Official Title

A Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin Gallate Supplementation on Serum Brain Derived Neurotrophic Factor and Mood Disturbance in Adults

Quick Facts

Study Start:2024-09-30
Study Completion:2025-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06531863

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adults age 18-50
  2. * Depression subscale score of \>9/21 on the DASS-21
  3. * No change in medications or supplements over the past 3 months
  4. * Can read and speak English
  1. * Currently consume curcumin or green tea daily
  2. * Currently, pregnant, nursing, or trying to become pregnant
  3. * Currently diagnosed with a perimenopausal disorder

Contacts and Locations

Study Contact

Aidan Cavanah, MSc
CONTACT
2057893258
amc0108@auburn.edu
Andrew Fruge, PhD
CONTACT
adf0003@auburn.edu

Principal Investigator

Andrew D Fruge, PhD
PRINCIPAL_INVESTIGATOR
Auburn University

Study Locations (Sites)

Auburn University School of Kinesiology
Auburn, Alabama, 36849
United States

Collaborators and Investigators

Sponsor: Auburn University

  • Andrew D Fruge, PhD, PRINCIPAL_INVESTIGATOR, Auburn University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-09-30
Study Completion Date2025-08-01

Study Record Updates

Study Start Date2024-09-30
Study Completion Date2025-08-01

Terms related to this study

Additional Relevant MeSH Terms

  • Mood Disturbance