RECRUITING

Multifocal HD-tDCS and Motor Function

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (HD-tDCS) can alter brain processes to improve behavior. Participants in this study will be randomized to either HD-tDCS with standard intervention or personalized dose-controlled multifocal network-targeted HD-tDCS. The hypothesis is that dexterous hand function will improve after a standard HD-tDCS dose and increase even more after personalized dose-controlled multifocal network-targeted HD-tDCS.

Official Title

Personalizing Multifocal Transcranial Direct Stimulation Dose to Target the Motor Network in Older Adults

Quick Facts

Study Start:2025-02-25
Study Completion:2025-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06561165

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:65 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participants should be in good health with normal or corrected-to-normal visual acuity
  2. * Right handed
  3. * No history of neurological disorder
  4. * English speaker
  5. * Able to provide written consent prior to admission
  1. * Left-handed
  2. * Participants are pregnant, suspect pregnancy or are attempting to become pregnant
  3. * Have a pacemaker, intracardiac lines or any other medically implanted device or medicine pump
  4. * Have cochlear hearing implants
  5. * Taking drugs known to influence neural receptors that facilitate neuroplasticity (see protocol)
  6. * Have non removable body piercings or have foreign objects in body
  7. * Have metal anywhere in the head that could increase risk of serious injury (not including braces, dental fillings, etc.) (see protocol)
  8. * Have a personal or family history of seizure/epilepsy
  9. * Taking prescription drugs that lower the threshold for seizures
  10. * Recent history of excessive alcohol consumption
  11. * History of alcohol addiction/dependence
  12. * Recent history of recreational drug use
  13. * History of drug addiction/dependence
  14. * Recent history of recreational drug use
  15. * History of drug addiction/dependence
  16. * Diagnosed with a stroke, brain hemorrhage, brain tumor, encephalitis.
  17. * Diagnosed with multiple sclerosis
  18. * Diagnosed with Parkinson's disease or Alzheimer's disease
  19. * Diagnosed with depression in the past 6 months
  20. * Diagnosed with attention deficit disorder, schizophrenia, manic depressive (bipolar) disorder
  21. * Diagnosed with normal pressure hydrocephalus or increased intra-cranial pressure
  22. * Diabetes requiring insulin treatment
  23. * Any serious heart disorder or liver disease

Contacts and Locations

Study Contact

Michael Vesia, PhD
CONTACT
734-764-5237
mvesia@umich.edu

Principal Investigator

Michael Vesia, PhD
PRINCIPAL_INVESTIGATOR
University of Michigan

Study Locations (Sites)

University of Michigan
Ann Arbor, Michigan, 48109
United States

Collaborators and Investigators

Sponsor: University of Michigan

  • Michael Vesia, PhD, PRINCIPAL_INVESTIGATOR, University of Michigan

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-25
Study Completion Date2025-05

Study Record Updates

Study Start Date2025-02-25
Study Completion Date2025-05

Terms related to this study

Keywords Provided by Researchers

  • Functional Magnetic Resonance Imaging (fMRI)
  • High-density transcranial direct current stimulation
  • manual dexterity
  • Non-invasive brain stimulation

Additional Relevant MeSH Terms

  • Healthy