RECRUITING

Satiety and Alcohol Challenge

Description

The goal of this pilot study is to identify the role of satiety on responses to alcohol drinking using human subject laboratory methods. Satiety will be manipulated over two sessions using a dietary supplement (fiber+green tea) or a calorically matched placebo. Responses to an acute alcohol challenge are measured.

Conditions

Alcohol Drinking
Talk to us

Related Conditions:

Alcohol Drinking

Study Overview

On this page

Study Details

Study overview

The goal of this pilot study is to identify the role of satiety on responses to alcohol drinking using human subject laboratory methods. Satiety will be manipulated over two sessions using a dietary supplement (fiber+green tea) or a calorically matched placebo. Responses to an acute alcohol challenge are measured.

Effect of a Dietary Supplement on Satiety and Acute Responses to Laboratory Alcohol Challenge

Satiety and Alcohol Challenge

Condition
Alcohol Drinking
Intervention / Treatment

-

Contacts and Locations

Chapel Hill

University of North Carolina, Chapel Hill, North Carolina, United States, 27599

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 21-45
  • * Meeting NIAAA criteria for current at-risk drinking (i.e., \>7/14 drinks in one week for women/men, with at least one episodes of 4+/5+ drinks in the past 30 days)
  • * Willingness to complete laboratory sessions involving blood draws and alcohol administration
  • * Ability to communicate and read in English
  • * Body mass index (BMI) of 21 - 30 kg/m\^2
  • * Meets past-year criteria for severe Alcohol Use Disorder (\>7 of 11 symptoms endorsed) or AUDIT score of 20+
  • * Meeting past-year criteria for a substance use disorder (with the exception of alcohol, tobacco or mild cannabis use disorder)
  • * Current engagement in alcohol treatments, or currently engaged in intentional efforts to quit alcohol use
  • * Current use of weight control medications
  • * Lifetime diagnosis of severe mental illness (including schizophrenia and bipolar disorder)
  • * History of suicide attempt, or psychiatric hospitalization in the last 6 months
  • * History of diabetes
  • * Medical conditions or medications for which alcohol is contraindicated
  • * Pregnant, nursing, or trying to become pregnant
  • * Plans to travel during the duration of study participation

Ages Eligible for Study

21 Years to 45 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of North Carolina, Chapel Hill,

Jimikaye Courtney, PhD, PRINCIPAL_INVESTIGATOR, University of North Carolina, Chapel Hill

Study Record Dates

2025-07