RECRUITING

Strength Training and Resveratrol

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The main goal of this study is to find out if supplementing with resveratrol improves skeletal muscle adaptations to strengthening exercise (resistance training or strength training) in adults age 60+, and to determine whether circulating vehicles of inter-organ communication (extracellular vesicles) and their cargo might help explain those responses. The investigators will also examine whether resveratrol supplementation improves blood vessel function and cognitive function (brain health) in response to strength training.

Official Title

Resveratrol-mediated Changes in Extracellular Vesicle microRNA Cargo as a Novel Contributor to Resistance Training-induced Skeletal Muscle Adaptations in Older Adults

Quick Facts

Study Start:2025-06-13
Study Completion:2026-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06585865

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 60+
  2. * Minimally active (less than 1 hour of structured exercise/week other than walking)
  3. * No resistance training for the previous 6 months
  4. * Not currently taking resveratrol supplements
  5. * Stable medication, supplement, dietary, and physical activity regimens for the previous 3 months and no plans to change throughout the study period
  6. * Body mass at least 110 lbs
  1. * Medical complications that could increase risk during exercise (e.g., cardiovascular disease, uncontrolled hypertension, type 1 or 2 diabetes, orthopedic contraindication to exercise, kidney disease, etc.)
  2. * Cannabis or nicotine use
  3. * Consume more than 7 alcohol-containing beverages per week

Contacts and Locations

Study Contact

Danielle E Levitt, PhD
CONTACT
806-834-1830
danielle.levitt@ttu.edu
Jacob A Mota, PhD
CONTACT
806-834-8772
jacob.mota@ttu.edu

Principal Investigator

Danielle E Levitt, PhD
PRINCIPAL_INVESTIGATOR
Texas Tech University

Study Locations (Sites)

Department of Kinesiology & Sport Management, Texas Tech University
Lubbock, Texas, 79409
United States

Collaborators and Investigators

Sponsor: Texas Tech University

  • Danielle E Levitt, PhD, PRINCIPAL_INVESTIGATOR, Texas Tech University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-13
Study Completion Date2026-08

Study Record Updates

Study Start Date2025-06-13
Study Completion Date2026-08

Terms related to this study

Keywords Provided by Researchers

  • Resistance training
  • Aging
  • Resveratrol
  • Sarcopenia
  • Extracellular Vesicles
  • MicroRNAs

Additional Relevant MeSH Terms

  • Sarcopenia
  • Anabolic Resistance