RECRUITING

Eating Disorders Genetics Initiative 2

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.

Official Title

Eating Disorders Genetics Initiative 2

Quick Facts

Study Start:2024-10-28
Study Completion:2027-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06594913

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:12 Years to 99 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms
  2. * Age 12-99 years, depending on country. (US enrollment age is 18-99)
  1. * History of subthreshold disordered eating behaviors.

Contacts and Locations

Study Contact

Laura M Thornton, PhD
CONTACT
804-690-3079
laura_thornton@med.unc.edu
Casey Macdermod, BA
CONTACT
984-974-3798
edgi2@unc.edu

Principal Investigator

Cynthia Bulik, PhD
PRINCIPAL_INVESTIGATOR
University of North Carolina, Chapel Hill

Study Locations (Sites)

University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599-7160
United States

Collaborators and Investigators

Sponsor: University of North Carolina, Chapel Hill

  • Cynthia Bulik, PhD, PRINCIPAL_INVESTIGATOR, University of North Carolina, Chapel Hill

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-28
Study Completion Date2027-08-01

Study Record Updates

Study Start Date2024-10-28
Study Completion Date2027-08-01

Terms related to this study

Keywords Provided by Researchers

  • severe and enduring eating disorder
  • genetics
  • mental health
  • disordered eating
  • environmental factors

Additional Relevant MeSH Terms

  • Anorexia Nervosa
  • Bulimia Nervosa
  • Binge-Eating Disorder
  • Avoidant Restrictive Food Intake Disorder