RECRUITING

Somatic Dysfunction in Patients With Acute Cerebrovascular Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goals of this observational study are to test the reliability of a new, standardized physical examination method to identify motion problems within joints or groups of joints among adult asymptomatic volunteers and in patients hospitalized with stroke or stroke-like episodes (e.g., transient ischemic attack, TIA). The main questions this investigation aims to answer are: * Can different, independent providers reliability quantify motion pattern problems using a systematic approach called, The Functional Pathology of the Musculoskeletal System (FPMSS) model? * Are there differences in joint(s) motion patterns among asymptomatic volunteers, patients with TIA (people with brain disease without new neurologic disability), and recent ischemic stroke (patients with new stroke-related-disability, e.g., paralysis)? * Is there an association between joint(s) motion impairment severity and stroke survivor outcomes? Participants (asymptomatic and those with stroke) will undergo a set of repeated paired, musculoskeletal physical exams by independent providers blinded to each other's assessments and patient information. Researchers will compare the severity, location, and quantity of joint(s) motion impairment between these three groups with the physical examination methodology (FPMSS). Clinical information (e.g., test results, diagnoses, brain imaging, medical history) will be collected from patients admitted for TIA and stroke. Enrolled participants with recent stroke will complete a survey three months after hospitalization to determine their self-perceived quality-of-life.

Official Title

Characterization of Somatic Dysfunction in Patients With Acute Cerebrovascular Disease

Quick Facts

Study Start:2023-09-01
Study Completion:2025-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06605014

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * adults ≥18 years
  2. * ischemic stroke OR
  3. * transient ischemic attack (TIA). A prior history of TIA but without stroke may be enrolled.
  4. * Neurologic stability or lack of significant deterioration (i.e. ∆ NIHSS\<4) for at least 24 hours (defined by clinical documentation and/or communication with provider team(s)) in stroke subjects
  5. * Able to sit upright, lie supine, and when able lateral recumbent left/right positions with assist independently or with minimal person assist
  6. * Anticipated length of stay greater \> or = 2 days for ischemic stroke. TIA patients average length of stay is \< 2 days, and can be enrolled in the study.
  1. * Acute skeletal fracture or known dislocation; history of pathologic (osteoporotic or neoplastic) skeletal fracture of thoracic cage, hip/pelvis/sacrum, or vertebral column
  2. * Prior history of ICH, ischemic stroke, confirmed by imaging and/or clinical evaluation. Patients with imaging showing "chronic stroke" who have never received a diagnosis of stroke and/or have not been previously symptomatic may still be enrolled, based on the Investigator's clinical judgement.
  3. * Spinal column support brace (e.g. cervical collar)
  4. * Anticipated neurosurgical intervention during hospitalization: decompressive hemicraniectomy, hematoma evacuation (defined by clinical documentation and/or communication with provider team(s))
  5. * Current endotracheal intubation (\*note: extubated patients can be evaluated for eligibility)
  6. * History of spinal cord injury with residual neuromuscular or sensory disability
  7. * History of recent trauma within the past 30 days
  8. * Known ligament, musculotendinous, or bone lesion
  9. * Clinical condition that would interfere with execution of movement or palpatory diagnostic testing, e.g. chronic pain
  10. * History of spinal surgery

Contacts and Locations

Study Contact

Alan Yee, D.O.
CONTACT
916-734-3588
ahyee@ucdavis.edu

Principal Investigator

Alan Yee, D.O.
PRINCIPAL_INVESTIGATOR
University of California, Davis

Study Locations (Sites)

University of California Davis Medical Center
Sacramento, California, 95817
United States

Collaborators and Investigators

Sponsor: University of California, Davis

  • Alan Yee, D.O., PRINCIPAL_INVESTIGATOR, University of California, Davis

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-01
Study Completion Date2025-05-31

Study Record Updates

Study Start Date2023-09-01
Study Completion Date2025-05-31

Terms related to this study

Additional Relevant MeSH Terms

  • Stroke, Acute
  • TIA
  • Reproducibility of Results
  • Osteopathic Manipulation
  • Health-Related Quality-of-Life