RECRUITING

Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a single-center, non-interventional, observational study that evaluates the correlation of circulating tumor DNA (ctDNA) testing to cancer relapse for participants with squamous cell carcinomas (HNC) of the head and neck mucosa and skin after curative-intent primary radiation or surgery.

Official Title

Tumor-informed ctDNA Testing for Minimal Residual Disease Monitoring Following Curative-intent Treatment of Squamous Cell Carcinoma of the Head and Neck.

Quick Facts

Study Start:2024-10-09
Study Completion:2029-12-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06606028

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Participants must have histologically or cytologically confirmed squamous cell carcinoma of the head and neck mucosa and skin.
  2. 2. Participants must be age \>=18 years.
  3. 3. Participants must be planning to receive curative-intent surgery or radiation-based treatment as part of standard of care treatment.
  4. 4. Participants must have the ability to understand and the willingness to sign a written informed consent document.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Sonia Contreras Martinez
CONTACT
415-514-6427
sonia.contrerasmartinez@ucsf.edu

Principal Investigator

Jason W Chan, MD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco

Study Locations (Sites)

University of California, San Francisco
San Francisco, California, 94143
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Jason W Chan, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-09
Study Completion Date2029-12-30

Study Record Updates

Study Start Date2024-10-09
Study Completion Date2029-12-30

Terms related to this study

Keywords Provided by Researchers

  • ctDNA

Additional Relevant MeSH Terms

  • Squamous Cell Carcinoma of Head and Neck
  • Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
  • Squamous Cell Carcinoma of Skin
  • Cutaneous Squamous Cell Carcinoma (CSCC)