RECRUITING

Effects of E-cigarette Use on Health

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown. This research proposal will quantify the effects of long-term ENDS use on validated and novel biomarkers of cardiovascular and pulmonary disease and how they are influenced by use heaviness, age, body weight, and co-use of other products. This study will produce the most informative evidence to date on how long-term ENDS use affects cardiovascular and pulmonary health.

Official Title

Longitudinal Effects of E-cigarette Use on Cardiovascular and Pulmonary Health

Quick Facts

Study Start:2025-01-06
Study Completion:2029-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06610838

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * greater than or equal to 21 years of age
  2. * has vaped a nicotine e-cigarette product at least 4 days/week for most weeks for greater than or equal to 12 months
  3. * plans to remain in catchment area for greater than or equal to 3 years
  4. * smoked 5 or fewer tobacco cigarettes in the past 6 months
  5. * no serious CV, pulmonary, or other medical problems
  6. * not currently pregnant
  7. * no plans to stop vaping
  1. * serious CV, pulmonary, or other medical problems (e.g., moderate or severe aortic stenosis, class III or IV heart failure, blood pressure greater than or equal to 160/100 mmHg, interstitial lung disease, sarcoidosis, Stage 3 or 4 cancer)
  2. * combusted or vaped cannabis use 3 days/week or more in the past 3 months
  3. * currently pregnant
  4. * not able to read an write English
  5. * incarceration

Contacts and Locations

Study Contact

James Stein, MD
CONTACT
608-262-2075
jhs@medicine.wisc.edu
Timothy Baker, PhD
CONTACT
503-387-5167
tbb@ctri.wisc.edu

Principal Investigator

Timothy Baker, PhD
PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison

Study Locations (Sites)

UW Center for Tobacco Research and Intervention
Madison, Wisconsin, 53711
United States

Collaborators and Investigators

Sponsor: University of Wisconsin, Madison

  • Timothy Baker, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-06
Study Completion Date2029-06-30

Study Record Updates

Study Start Date2025-01-06
Study Completion Date2029-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Electronic Cigarette Use