RECRUITING

Ultrasound Neuromodulation in Essential Tremor

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU can be a useful tool for studying the brain circuits responsible for tremor and other brain disorders.

Official Title

Ultrasound Neuromodulation in Essential Tremor

Quick Facts

Study Start:2024-10
Study Completion:2027-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06610877

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients with medically refractory tremor scheduled to undergo MR-guided high-intensity focused ultrasound (HIFU) thalamotomy to treat their tremor at UCSF.
  1. * Due to the logistical complexity of performing MRI in patients with MR-conditional pacemakers (need for device and patient monitoring), patients with pacemakers will be excluded from enrollment. All other patients undergoing HIFU thalamotomy for tremor will be eligible for enrollment.

Contacts and Locations

Study Contact

Leo P. Sugrue, MD, PhD
CONTACT
415-353-9056
leo.sugrue@ucsf.edu
Tommaso Di Ianni, PhD
CONTACT
tommaso.diianni@ucsf.edu

Principal Investigator

Leo Sugrue, MD, PhD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco

Study Locations (Sites)

Pritzker Building, UCSF
San Francisco, California, 94107
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Leo Sugrue, MD, PhD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10
Study Completion Date2027-03

Study Record Updates

Study Start Date2024-10
Study Completion Date2027-03

Terms related to this study

Keywords Provided by Researchers

  • Essential Tremor
  • Neuromodulation
  • Focused Ultrasound
  • brain functional connectivity

Additional Relevant MeSH Terms

  • Essential Tremor
  • Neuromodulation