RECRUITING

Screening Strategies Among High-risk Populations for Anal Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.

Official Title

Screening Strategies Among High-risk Populations for Anal Cancer

Quick Facts

Study Start:2024-12-16
Study Completion:2027-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06628570

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:30 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 30-80 years of age
  2. * Individuals with chronic impaired immune status
  3. * History of high-grade lower genital tract neoplasia (LGTN), Zubrod Performance Status of 0-2;
  1. * Patients treated for aHSIL less than 6 months before screening,
  2. * History of anal cancer and pregnant women.

Contacts and Locations

Study Contact

Lisa Flowers, MD, MPH
CONTACT
404-251-8931
lflowe2@emory.edu

Principal Investigator

Lisa Flowers, MD, MPH
PRINCIPAL_INVESTIGATOR
Emory University
Canhua Xiao, PhD, RN
PRINCIPAL_INVESTIGATOR
Emory University

Study Locations (Sites)

University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136
United States
University of Miami School of Medicine at Jackson Memorial Hospital (JMH)
Miami, Florida, 33136
United States
Grady Memorial Hospital
Atlanta, Georgia, 30303
United States
The Ponce Center
Atlanta, Georgia, 30308
United States

Collaborators and Investigators

Sponsor: Lisa Flowers

  • Lisa Flowers, MD, MPH, PRINCIPAL_INVESTIGATOR, Emory University
  • Canhua Xiao, PhD, RN, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-16
Study Completion Date2027-10

Study Record Updates

Study Start Date2024-12-16
Study Completion Date2027-10

Terms related to this study

Keywords Provided by Researchers

  • Cancer
  • HIV
  • Screening

Additional Relevant MeSH Terms

  • Neoplasms
  • HPV-Related Anal Squamous Cell Carcinoma