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JIT: Effect of Pain on DT in TMD

Description

Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and non-modifiable risk factors, including orofacial pain status, have been conducted. This project addresses this gap in knowledge by determining the effect of pain on drinking topography in heavy drinkers with and without chronic TMD pain in both the laboratory and daily life.

Conditions

Temporomandibular Disorder (TMD)
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Related Conditions:

Temporomandibular Disorder (TMD)

Study Overview

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Study Details

Study overview

Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and non-modifiable risk factors, including orofacial pain status, have been conducted. This project addresses this gap in knowledge by determining the effect of pain on drinking topography in heavy drinkers with and without chronic TMD pain in both the laboratory and daily life.

JIT: Effects of Pain on Laboratory Drinking Topography and Daily Drinking in People With Chronic Temporomandibular Disorder (TMD) Pain

JIT: Effect of Pain on DT in TMD

Condition
Temporomandibular Disorder (TMD)
Intervention / Treatment

-

Contacts and Locations

Minneapolis

University of Minnesota, Minneapolis, Minnesota, United States, 55414

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants in this study must be 21 years to 65 years of age and provide a driver's license or other state-issued ID.
  • * Participants must also be sufficiently fluent in English to provide informed consent and understand questionnaires and instructions for laboratory procedures.
  • * Participants in this study must report regular drinking exceeding NIAAA guidelines for (≥ 2 (men) or ≥ 1 (women) drinks per day on average) over the past six months, as well as drinking on ≥ 2 days/week.
  • * Meet Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for myalgia (masticatory muscle pain), arthralgia (TMJ pain), or a combination (Schiffman et al., 2014) (TMD group only).
  • * Own a smartphone with internet access.
  • * Use of prescription medications will be allowed, provided they do not contraindicate alcohol use.
  • * Use of opioid analgesics within the past month;
  • * Current major depression;
  • * History of any psychotic disorder;
  • * Under-controlled hypertension or diabetes (as reflected by self-report); neurological disease (e.g., multiple sclerosis, epilepsy, amyotrophic lateral sclerosis, Parkinson's disease);
  • * Serious medical illness (e.g., hepatitis, HIV/AIDS);
  • * Impaired cognitive function;
  • * History of substance use disorder (including nicotine/tobacco);
  • * Alcohol naïve
  • * Alcohol use disorder, or currently attempting to quit or cut down on using alcohol
  • * Positive pregnancy test
  • * Breastfeeding or intending to become pregnant
  • * Loss of sensation in the lower leg
  • * Inability to complete study tasks due to weakness, immobilization, or loss of limbs
  • * Chronic pain (Control group only)
  • * A urine-based drug screen for tetrahydrocannabinol, cocaine, benzodiazepines, morphine, and methamphetamine (Innovacon, Inc., San Diego, CA) will be performed. Participants testing positive for any substance will be discontinued.
  • * Medications that contraindicate alcohol use

Ages Eligible for Study

21 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Minnesota,

Jeff Boissoneault, PRINCIPAL_INVESTIGATOR, University of Minnesota

Study Record Dates

2029-09-07