RECRUITING

Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic Stroke

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This research study aims to understand the relationship between brain stimulation and leg skill learning in both healthy adults and persons with chronic stroke.

Official Title

An Exploratory Study: The Effects of Cortical Priming on Visuomotor Stepping Learning in Healthy Adults and Persons With Chronic Stroke

Quick Facts

Study Start:2025-04-23
Study Completion:2026-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06681207

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Age between 21 and 90 years
  2. 2. Medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment
  3. 3. MRI or CT evidence from the imaging report shown that the stroke involves the corticospinal tract
  4. 4. Hemiparesis involving the lower extremity (Fulg-Meyer LE motor test)
  5. 5. No passive range of motion limitation in bilateral hips and knees
  6. 6. Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less
  7. 7. Visual acuity can be corrected by glasses or contact lens to 20/20
  8. 8. Able to walk independently with/without assistant devices for 10 meters
  9. 9. Able to maintain standing position without any assistance \> 30 sec (Short Physical Performance Battery)
  10. 10. Evaluation of cognitive status: Mini-mental status examination (MMSE) score ≥ 24
  1. 1. Pregnant women
  2. 2. MRI or CT evidence of involvement of the basal ganglia or cerebellum, evidence of multiple lesions, or evidence of any other brain damage or malignant neoplasm or tumors
  3. 3. Have any metal implants, cardiac pacemakers, or history of seizures
  4. 4. Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training
  5. 5. Any vestibular dysfunction or unstable angina
  6. 6. Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia\*

Contacts and Locations

Study Contact

Shih-Chiao Tseng, PT, PhD
CONTACT
409--772-9555
shtseng@utmb.edu

Principal Investigator

Shih-Chiao Tseng, PT, PhD
PRINCIPAL_INVESTIGATOR
University of Texas

Study Locations (Sites)

Physical Therapy, University of Texas Medical Branch
Galveston, Texas, 77555
United States

Collaborators and Investigators

Sponsor: The University of Texas Medical Branch, Galveston

  • Shih-Chiao Tseng, PT, PhD, PRINCIPAL_INVESTIGATOR, University of Texas

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-23
Study Completion Date2026-10

Study Record Updates

Study Start Date2025-04-23
Study Completion Date2026-10

Terms related to this study

Keywords Provided by Researchers

  • adult
  • chronic stroke

Additional Relevant MeSH Terms

  • Stroke