RECRUITING

Predict Tooth Wear

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Tooth wear, resulting from gradual loss of dental hard tissue due to mechanical and chemical factors, impacts tooth structure, texture, and function. It affects quality of life, with varying prevalence (26.9% to 90.0%), and is traditionally detected visually during check-ups, often at advanced stages. Monitoring alterations in tooth shape via intraoral scanners aids early detection, but restoration remains challenging. Prevention through early detection is vital, as patients may not fully comprehend tooth structure loss until visible. Recently, statistical shape analysis (SSA) used to learn the tooth anatomy and define a reference shape (biogeneric tooth) using. However, assuring landmark consistency is challenging mostly due to biases of the operator. Recently, a robust method called MEG-IsoQuad offered automated, isotopological remeshing. Combining this with SSA holds promise for diagnostic and simulation purposes. This study aims to assess the reliability of a remeshing-SSA approach for altered and intact premolar analysis and compare machine learning algorithms for simulating the shape of the initially intact tooth or future altered one. The clinical perspective of the current work offers possibilities to: * Prevent future tooth wear by detecting it at an early stage; and communicate better to the patient by presenting him/her potential future altered teeth * Simulate the adapted reconstruction for the altered tooth by simulating the initially intact one

Official Title

Prediction of the Tooth Wear Index Based on a Dataset of Dental Shapes:a Retrospective Study

Quick Facts

Study Start:2023-12-12
Study Completion:2027-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06681844

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * teeth avulsed presenting a tooth wear index between 0 and 3
  2. * mature incisor, canine, premolar or molars (1st and 2nd only)
  1. * teeth avulsed presenting a tooth wear index over 3 (or presenting an oral rehabilitation representative of a similar wear)
  2. * immature teeth or teeth without root edification
  3. * wisdom teeth

Contacts and Locations

Study Contact

Raphael Richet, Clinical Assistant
CONTACT
+33669523314
raphael.richert@univ-lyon1.fr
Maxime Ducret, Professor
CONTACT
maxime.ducret@univ-lyon1.fr

Study Locations (Sites)

Indiana University Hospital
Indianapolis, Indiana, 46202
United States

Collaborators and Investigators

Sponsor: Hospices Civils de Lyon

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-12-12
Study Completion Date2027-12

Study Record Updates

Study Start Date2023-12-12
Study Completion Date2027-12

Terms related to this study

Additional Relevant MeSH Terms

  • Prediction of Tooth Wear