RECRUITING

Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The proposed study seeks to understand how the cervical spinal cord should be stimulated after injury through short-term physiology experiments that will inform a preclinical efficacy trial. The purpose of this study is to determine which cervical levels epidural electrical stimulation (EES) should target to recruit arm and hand muscles effectively and selectively in spinal cord injury (SCI).

Official Title

Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery

Quick Facts

Study Start:2024-12-06
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06701422

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Jason B Carmel, M.D., Ph.D.
CONTACT
917-301-1882
jbc28@cumc.columbia.edu
James R McIntosh, Ph.D.
CONTACT
212-305-6616
jrm2263@cumc.columbia.edu

Study Locations (Sites)

Columbia University Irving Medical Center
New York, New York, 10032
United States
The Daniel and Jane Och Spine Hospital at NewYork-Presbyterian/Allen
New York, New York, 10034
United States

Collaborators and Investigators

Sponsor: Columbia University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-06
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2024-12-06
Study Completion Date2026-06-30

Terms related to this study

Keywords Provided by Researchers

  • spinal cord injury
  • upper-limb muscle activation
  • cervical spinal cord
  • myelopathy

Additional Relevant MeSH Terms

  • Cervical Spinal Cord Injury
  • Tetraplegia/Tetraparesis
  • Cervical Myelopathy