RECRUITING

Quantitative Ultrasound to Assess Steatotic Liver Disease in Children

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This research study is being conducted to find out more about advanced ultrasound techniques to non-invasively evaluate liver disease in children. The investigators are developing advanced techniques for analyzing ultrasound data and images of the liver, and they will compare it to other established methods used to evaluate the liver, including liver MRI. The investigators plan to develop and test the advanced analysis techniques using conventional full-size ultrasound machines and, if possible, small handheld devices. Our goals are: * To assess the accuracy of the advanced ultrasound analysis techniques in children * To implement and assess these advanced technique on small handheld ultrasound devices, if possible

Official Title

Quantitative Ultrasound to Assess Steatotic Liver Disease in Children

Quick Facts

Study Start:2024-09-23
Study Completion:2029-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06706856

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:9 Years to 18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 9 to 18 years
  2. * Presence of risk factors for having MASLD
  3. * Ability and willingness of participant or legal guardian/parent to give written informed consent
  4. * Participant is willing to give written assent
  5. * Able and willing to undergo all study procedures
  1. * Known liver disease other than MASLD
  2. * Pregnant or trying to become pregnant
  3. * Inability to undergo an MR study: weight exceeding scanner table limit, waist circumference \> 140 cm, claustrophobie, and/or metal implants.

Contacts and Locations

Study Contact

Amy Alba
CONTACT
619-543-5228
amalba@health.ucsd.edu
Gage Tanzman
CONTACT
g1tanzman@health.ucsd.edu

Principal Investigator

Jeffrey B Schwimmer, MD
PRINCIPAL_INVESTIGATOR
University of California, San Diego
Claude B Sirlin, MD
PRINCIPAL_INVESTIGATOR
University of California, San Diego

Study Locations (Sites)

University of California San Diego
La Jolla, California, 92037
United States

Collaborators and Investigators

Sponsor: University of California, San Diego

  • Jeffrey B Schwimmer, MD, PRINCIPAL_INVESTIGATOR, University of California, San Diego
  • Claude B Sirlin, MD, PRINCIPAL_INVESTIGATOR, University of California, San Diego

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-09-23
Study Completion Date2029-06-30

Study Record Updates

Study Start Date2024-09-23
Study Completion Date2029-06-30

Terms related to this study

Keywords Provided by Researchers

  • MASLD
  • steatosis
  • quantitative ultrasound
  • quantitative MRI
  • fat fraction
  • PDFF

Additional Relevant MeSH Terms

  • MASLD
  • MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease