Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Males and females age 21 years or older.
- * Able and willing to provide written informed consent.
- * Hospitalization or doctor's visits within prior 30 days, except for routine checkup/physical examination.
- * Use of antiplatelet therapy within the past 7 days, e.g. aspirin, clopidogrel, prasugrel, ticagrelor, cilostazol.
- * Use of anticoagulant drugs within the past 7 days, e.g. heparin, bivalirudin, warfarin, rivaroxaban, and apixaban.
- * Use of certain nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit COX-1 such as naproxen or ibuprofen within the past 3 days, unless confirmed to not inhibit platelet activity (such as celecoxib).
- * History of anemia.
- * Known thrombocytopenia (platelet count \< 100,000/μL).
- * Significant renal dysfunction or dialysis.
- * History of platelet disorders e.g. von Willebrand factor deficiency, Glanzmann's thrombasthenia or Bernard-Soulier syndrome.
- * History of hemophilia or bleeding disorders.
- * Known active gastrointestinal disease including peptic ulcers, gastro-esophageal reflux disease (GERD), and hyperacidity.
- * Currently participating in a study involving an investigational drug or compound known to affect coagulation or hemostasis.
- * Subjects with significant past medical history as determined by the Investigator that would pose safety concerns or interfere with the study goals.
Ages Eligible for Study
21 Years to
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
No