RECRUITING

Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training

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Conditions

MenopauseHot FlashesBlood Pressure Regulationblood pressureinspiratory training

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research is to understand how training the muscles used for breathing (inhalation) affects menopausal hot flashes, sympathetic nerve activity and sleep.

Official Title

Time-efficient Inspiratory Muscle Strength Training for Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women

Quick Facts

Study Start:2025-03-27
Study Completion:2027-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06743269

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:45 Years to 60 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Females aged 45-60 with hot flashes.
  2. * Participants will be recruited from Rochester, MN and surrounding areas.
  3. * Non-smokers.
  4. * BMI \< 40kg/m\^2.
  5. * No history of cardiovascular disease, except for hypertension.
  1. * Detailed medical and social histories will be collected. To allow for ecological validity, participants will not be excluded for use of menopausal hormone therapy or medications affecting cardiovascular function so long as they have been on a consistent regimen for ≥3 months and during the study period. This approach to medications is consistent with recent work in this area.
  2. * Participants will be screened for contraindications to inspiratory muscle strength training including, a history of spontaneous pneumothorax, collapsed lung that has not healed fully, a perforated eardrum that has not healed fully, and/or any other condition of the eardrum.
  3. * Additional exclusion criteria will include the use of sleep aids (i.e., prescription, melatonin, doxylamine, valerian root, etc.).

Contacts and Locations

Study Contact

Pamela Engrav
CONTACT
(507) 255-6938
engrav.pamela@mayo.edu
Nancy Meyer
CONTACT
507-255-0913
meyer.nancy2@mayo.edu

Principal Investigator

Sarah Baker, PhD
PRINCIPAL_INVESTIGATOR
Mayo Clinic

Study Locations (Sites)

Mayo Clinic in Rochester
Rochester, Minnesota, 55905
United States

Collaborators and Investigators

Sponsor: Mayo Clinic

  • Sarah Baker, PhD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-27
Study Completion Date2027-01

Study Record Updates

Study Start Date2025-03-27
Study Completion Date2027-01

Terms related to this study

Keywords Provided by Researchers

  • menopause
  • blood pressure
  • inspiratory training
  • hot flashes

Additional Relevant MeSH Terms

  • Menopause
  • Hot Flashes
  • Blood Pressure Regulation