RECRUITING

Machine-Learning Prediction and Reducing Overdoses with EHR Nudges

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this cluster randomized clinical trial is to test a clinician-targeted behavioral nudge intervention in the Electronic Health Record (EHR) for patients who are identified by a machine-learning based risk prediction model as having an elevated risk for an opioid overdose. The clinical trial will evaluate the effectiveness of providing a flag in the EHR to identify individuals at elevated risk with and without behavioral nudges/best practice alerts (BPAs) as compared to usual care by primary care clinicians. The primary goals of the study are to improve opioid prescribing safety and reduce overdose risk.

Official Title

Machine-Learning Prediction and Reducing Overdoses with EHR Nudges

Quick Facts

Study Start:2025-03-10
Study Completion:2026-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06806163

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Received an opioid prescription within the past year
  2. * Age 18 years or older at the time of the opioid prescription
  3. * At least one visit to an internal medicine or family care practice within the past year
  1. * Diagnosis of malignant cancer within the past year
  2. * Enrollment in hospice care

Contacts and Locations

Study Contact

Lead Research Program Coordinator, CP3
CONTACT
(412) 692-4889
cp3@pitt.edu

Principal Investigator

Walid F Gellad, MD, MPH
PRINCIPAL_INVESTIGATOR
University of Pittsburgh Center for Pharmaceutical Policy and Prescribing

Study Locations (Sites)

University of Pittsburgh
Pittsburgh, Pennsylvania, 15213
United States

Collaborators and Investigators

Sponsor: University of Pittsburgh

  • Walid F Gellad, MD, MPH, PRINCIPAL_INVESTIGATOR, University of Pittsburgh Center for Pharmaceutical Policy and Prescribing

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-10
Study Completion Date2026-03

Study Record Updates

Study Start Date2025-03-10
Study Completion Date2026-03

Terms related to this study

Keywords Provided by Researchers

  • Machine learning
  • Risk prediction
  • Behavioral nudge
  • Best Practice Alert
  • Artificial intelligence
  • Primary care
  • Electronic Health Record Platforms
  • Opioid Overdose
  • Opioids

Additional Relevant MeSH Terms

  • Opioid Overdose
  • Opioid Use
  • Opioid Use Disorder
  • Opioids