RECRUITING

Optimizing Strength Training in Older Adults

Conditions

Aging Strength training Older adults physical function

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of the current study is to determine whether lifting lighter loads close to failure improves strength training adaptations and function in older adults. The main questions it aims to answer are: 1. The effect of light loads on physical function 2. The effect of light loads on muscle mass, power, and strength Researchers will compare a light-load, high-repetition program to a standard strength training program. Participants will perform supervised strength training twice per week for 20 weeks.

Official Title

Optimizing Strength Training in Older Adults

Quick Facts

Study Start:2025-02-10

Study Completion:2027-06

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06812143

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:65 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Males and females aged 65 years and above * Inactive lifestyle (\< 150 min per week of moderate intensity physical activity) and not regularly participating in a structured strength training program * Planning to reside in the area for the duration of the study	* Severe cardiac disease, including Class III or IV congestive heart failure, clinically significant aortic stenosis, history of cardiac arrest, use of a cardiac defibrillator, or uncontrolled angina * Lung disease requiring either oral or injected steroids, or the use of supplemental oxygen * Short, portable mental status questionnaire with 3 or more errors * Severe arthritis (either osteoarthritis or rheumatoid arthritis) * Cancer requiring treatment in the past 1 year (melanomas excluded) * Development of chest pain or severe shortness of breath during the 6 min self-paced walk test * Parkinson's disease or other serious neurological disorders * Renal disease requiring dialysis * Current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder * Current consumption of more than 14 alcoholic drinks per week * Severe lower back or shoulder pain that may worsen with weightlifting exercises * Undergoing physical therapy involving the lower extremities * Living in nursing homes, assisted living facilities or other similar institutions * Currently enrolled in another randomized trial involving a pharmaceutical or lifestyle intervention * Weight change (intentional or not) over the last 6 months of \> 5% of body weight, or plan to lose or gain weight during the study * Any other cardiovascular, pulmonary, orthopedic, neurologic, or other conditions that would preclude participation and successful completion of the protocol * Severe hypertension, e.g., SBP \> 200 mm Hg, DBP \> 110 mm Hg * Major surgery or fracture or hip/knee replacement within the last 6 months * Hospitalization within the last 6 months (excluding ER visits)

Inclusion Criteria

Exclusion Criteria

* Males and females aged 65 years and above
* Inactive lifestyle (\< 150 min per week of moderate intensity physical activity) and not regularly participating in a structured strength training program
* Planning to reside in the area for the duration of the study

* Severe cardiac disease, including Class III or IV congestive heart failure, clinically significant aortic stenosis, history of cardiac arrest, use of a cardiac defibrillator, or uncontrolled angina
* Lung disease requiring either oral or injected steroids, or the use of supplemental oxygen
* Short, portable mental status questionnaire with 3 or more errors
* Severe arthritis (either osteoarthritis or rheumatoid arthritis)
* Cancer requiring treatment in the past 1 year (melanomas excluded)
* Development of chest pain or severe shortness of breath during the 6 min self-paced walk test
* Parkinson's disease or other serious neurological disorders
* Renal disease requiring dialysis
* Current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder
* Current consumption of more than 14 alcoholic drinks per week
* Severe lower back or shoulder pain that may worsen with weightlifting exercises
* Undergoing physical therapy involving the lower extremities
* Living in nursing homes, assisted living facilities or other similar institutions
* Currently enrolled in another randomized trial involving a pharmaceutical or lifestyle intervention
* Weight change (intentional or not) over the last 6 months of \> 5% of body weight, or plan to lose or gain weight during the study
* Any other cardiovascular, pulmonary, orthopedic, neurologic, or other conditions that would preclude participation and successful completion of the protocol
* Severe hypertension, e.g., SBP \> 200 mm Hg, DBP \> 110 mm Hg
* Major surgery or fracture or hip/knee replacement within the last 6 months
* Hospitalization within the last 6 months (excluding ER visits)

Contacts and Locations

Study Contact

Anoop T Balachandran, PhD

CONTACT

718-997-2729

athozhuthungalba@qc.cuny.edu

Study Locations (Sites)

Exercise & Aging Lab, Queens College

Flushing, New York, 11367

United States

Collaborators and Investigators

Sponsor: Queens College, The City University of New York

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-10

Study Completion Date2027-06

Study Record Updates

Study Start Date2025-02-10

Study Completion Date2027-06

Terms related to this study

Keywords Provided by Researchers

Strength training
Older adults
physical function

Additional Relevant MeSH Terms

Aging