RECRUITING

Mediators and Moderators of Auditory Training

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn how Auditory Training (AT) may help people better understand speech in noisy environments. As people get older, it becomes harder for them to hear speech clearly when there is background noise. This can be frustrating, and it can affect their independence and quality of life. AT is often used to support people with and without hearing loss, especially when a person is not a good candidate for a hearing aid or when amplification from a hearing aid does not improve performance. The investigators want to gather reliable data to understand how AT works and what affects its success. The main questions the trial aims to answer are: * How do different types of sounds influence the effectiveness of auditory training? * Which auditory training approaches are most successful in improving speech understanding? * How do personal traits impact the results of auditory training? The investigators will study a large and diverse group of 1,260 participants, including both young and older adults, to evaluate various auditory training approaches. You will: * Take part in auditory training sessions that include different types of auditory tasks. * Complete tests that measure how well they understand speech in both quiet and noisy settings. * Complete surveys on personal data like demographics, hearing challenges and other factors to help researchers understand what might influence training results. The investigators will measure and compare the results of these approaches to find out which ones are most effective. This could help people who are at risk of cognitive decline, like those at risk for Alzheimer's disease.

Official Title

Mediators and Moderators of Auditory Training

Quick Facts

Study Start:2025-01-06
Study Completion:2027-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06812273

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18-30 and 60-85 years of age.
  2. * No self-reported auditory difficulties and normal or near-normal hearing sensitivity as measured by SRTs.
  3. * Older adults aged 50-85 should have no more than typical hearing loss for their age and no evidence of dementia.
  4. * Fluent in English and/or Spanish
  1. * Abnormal vision or hearing prohibitive of training
  2. * History of seizures, focal brain lesion, or head injury with loss of consciousness
  3. * Physical handicap (motor or perceptual) that would impede training procedures
  4. * Medical illness requiring treatment during the study timeline
  5. * Social, educational or economic hardship prohibitive to training schedule
  6. * Concurrent enrollment in other cognitive training studies
  7. * History of major psychiatric illness, including psychosis, bipolar disorder, depression, alcohol or substance abuse, recent bereavement
  8. * Plans to travel out of the area for more than 1 week during the intervention period
  9. * Residence too far from the testing site, which would prevent attending the testing sessions (\> 60 miles)
  10. * Not being proficient enough in English or Spanish that would prevent following and understanding all instructions and completing all testing sessions
  11. * Diagnosis of dementia or other neurological disease, including mild cognitive impairment (MCI)
  12. * Telephone-Montreal Cognitive Assessment (t-MoCA) score of 16 or less or Montreal Cognitive AssessmentMoCA) score of 20 or less

Contacts and Locations

Study Contact

Audrey Carrillo, M.A.
CONTACT
626-482-8091
a.carrillo@northeastern.edu

Principal Investigator

Aaron Seitz, PhD
PRINCIPAL_INVESTIGATOR
Northeastern University
Tess Koerner, PhD
PRINCIPAL_INVESTIGATOR
Oregon Health and Science University

Study Locations (Sites)

University of California, Riverside
Riverside, California, 92521
United States
Northeastern University
Boston, Massachusetts, 02115
United States
Oregon Health & Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Northeastern University

  • Aaron Seitz, PhD, PRINCIPAL_INVESTIGATOR, Northeastern University
  • Tess Koerner, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-06
Study Completion Date2027-05-31

Study Record Updates

Study Start Date2025-01-06
Study Completion Date2027-05-31

Terms related to this study

Keywords Provided by Researchers

  • audition
  • auditory training
  • cognition

Additional Relevant MeSH Terms

  • Hearing Handicap