RECRUITING

Lipomas Treated with Subcutaneous Injections of Cooled Sodium Chloride

Description

Lipomas are benign tumors composed of mature adipose tissue. While harmless, these are the most common type of soft tissue growths with some patients developing numerous lipomas. Patients often seek removal for cosmesis, or symptoms caused by location and/or compression of surrounding structures. This exploratory study aims to evaluate the effectiveness of subcutaneous injections of cooled normal saline as a treatment option for lipomas. The study will assess whether this technique could serve as a viable alternative to existing treatment options, especially compared to topically applied fat-freezing devices. The Investigators propose that this method may offer a more comfortable nonsurgical option for targeted fat reduction, as the cold temperatures are applied directly to the lipomas.

Conditions

Study Overview

Study Details

Study overview

Lipomas are benign tumors composed of mature adipose tissue. While harmless, these are the most common type of soft tissue growths with some patients developing numerous lipomas. Patients often seek removal for cosmesis, or symptoms caused by location and/or compression of surrounding structures. This exploratory study aims to evaluate the effectiveness of subcutaneous injections of cooled normal saline as a treatment option for lipomas. The study will assess whether this technique could serve as a viable alternative to existing treatment options, especially compared to topically applied fat-freezing devices. The Investigators propose that this method may offer a more comfortable nonsurgical option for targeted fat reduction, as the cold temperatures are applied directly to the lipomas.

Lipomas Treated with Subcutaneous Injections of Cooled Sodium Chloride: an Exploratory Study

Lipomas Treated with Subcutaneous Injections of Cooled Sodium Chloride

Condition
Lipoma
Intervention / Treatment

-

Contacts and Locations

Morgantown

West Virginia University, Morgantown, West Virginia, United States, 26505

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * At least one clinically diagnosed subcutaneous lipoma
  • * Unable to give informed consent
  • * Participant has a lipoma on the face
  • * Lipomas located subfascial or within deep tissue (e.g., intramuscular lipomas)
  • * Lipomas larger than 10 cm in diameter (fat deposits exceeding 500 mL in volume)
  • * Rapidly growing lipomas
  • * Lipomas exhibiting abnormal ultrasound findings (e.g., complex hyperechoic patterns, internal heterogeneity, or multilobulated appearance)
  • * Pregnant women

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

West Virginia University,

Jessica Patterson, MD, PRINCIPAL_INVESTIGATOR, West Virginia University-Dermatology

Study Record Dates

2026-01