RECRUITING

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research is (1) to identify disease specific walking-related digital biomarkers of disease severity, and (2) monitor longitudinal changes in natural environments, for extended periods of time, in DMD and SMA.

Official Title

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

Quick Facts

Study Start:2024-05-01
Study Completion:2028-04-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06839469

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:5 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Jacqueline Montes, PT, EdD
CONTACT
212-305-8916
jm598@cumc.columbia.edu
Michael Lutzker
CONTACT
925-705-5133
ml5121@cumc.columbia.edu

Study Locations (Sites)

Stanford University
Palo Alto, California, 94304
United States
Boston Children's Hospital
Boston, Massachusetts, 02115
United States
Columbia University Irving Medical Center
New York, New York, 10032
United States

Collaborators and Investigators

Sponsor: Columbia University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-05-01
Study Completion Date2028-04-01

Study Record Updates

Study Start Date2024-05-01
Study Completion Date2028-04-01

Terms related to this study

Keywords Provided by Researchers

  • SMA
  • spinal muscular atrophy
  • duchenne muscular dystrophy
  • DMD
  • instrumented insole
  • neuromuscular disease
  • machine learning model
  • gait analysis
  • functional biomarker
  • wearable
  • six minute walk test
  • ambulatory
  • becker phenotype

Additional Relevant MeSH Terms

  • Spinal Muscular Atrophy Type 3
  • Duchenne Muscular Dystrophy (DMD)