RECRUITING

CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this feasibility study is to learn whether Cannabidiol (CBD) can improve urinary incontinence and other symptoms in people with recent spinal cord injury (SCI). Participants will take Epidiolex (purified CBD) for 90 days

Official Title

Cannabinoid Modulation for Neurogenic Lower Urinary Tract Dysfunction in Spinal Cord Injury

Quick Facts

Study Start:2025-07
Study Completion:2027-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06840899

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * \>18 years of age
  2. * History of supra-sacral spinal cord injury of any mechanism
  3. * Urinary incontinence with ≥2 episodes of urinary incontinence per day (outside of spinal shock)
  4. * Willingness to participate in drug intervention trial
  5. * English-speaking (able to provide consent and complete questionnaires)
  1. * History of intravesical Botox
  2. * Actively taking \>15 mg of Oxybutynin single dose or equivalent dose of alternative anticholinergic medication for bladder symptoms
  3. * Use of Cannabis (any form) outside of study as determined by urine drug screen after washout period of 1 month if prior Cannabis use reported
  4. * Thought or mood disorder aside from depression

Contacts and Locations

Study Contact

Maria Flory
CONTACT
608-262-8652
flory@ortho.wisc.edu

Principal Investigator

Javi Santiago
PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison

Study Locations (Sites)

University of Wisconsin - Madison
Madison, Wisconsin, 53705
United States

Collaborators and Investigators

Sponsor: University of Wisconsin, Madison

  • Javi Santiago, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07
Study Completion Date2027-01

Study Record Updates

Study Start Date2025-07
Study Completion Date2027-01

Terms related to this study

Additional Relevant MeSH Terms

  • Supra-sacral Spinal Cord Injury
  • Spinal Cord Injury
  • Urinary Incontinence