RECRUITING

Teaching Harm Reduction in a Hospital Setting: A Peer-led Intervention

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to develop an acceptable, feasible, and effective peer-led bundle of harm reduction services to be delivered in the hospital setting, called the THRIVE intervention. The main question it aims to answer is: Will participants receiving the THRIVE intervention have a reduced risk of self-reported non-fatal overdoses OR skin/soft tissue infections compared to participants receiving enhanced usual care? Researchers will compare the THRIVE model to enhanced usual care to see if the THRIVE model helps participants reduce their number of self-reported non-fatal overdoses OR skin/soft tissue infections. Intervention participants will: * Receive one in-person session from a peer support specialist while in the hospital * Receive weekly text messages from the peer support specialist for a 12-week period * Receive monthly, multiple-choice assessments via text message at Month 1, 2, 3, 4, 5, and 6 * Complete a baseline, 3-month, and 6-month assessment with Research Assistants Enhanced usual care participants will: * Receive a handout with harm reduction education and resources in their local area * Receive monthly, multiple-choice assessments via text message at Month 1, 2, 3, 4, 5, and 6 * Complete a baseline, 3-month, and 6-month assessment with Research Assistants

Official Title

Teaching Harm Reduction in Vulnerable Environments (THRIVE): A Peer-led Intervention Bridging Acute Care Settings and the Discharge to the Community

Quick Facts

Study Start:2025-02-18
Study Completion:2028-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06843213

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participants who are: a) admitted to University of Pittsburgh Medical Center (UPMC) Shadyside Hospital, UPMC Presbyterian-Montefiore Hospital, UPMC Mercy Hospital for inpatient or observation status, or b) seen in the Emergency Department setting at UPMC Presbyterian-Montefiore Hospital and UPMC Mercy Hospital.
  2. * Participants must have a current diagnosis of Opioid Use Disorder based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnostic criteria.
  3. * Participants must be at least 18 years of age on day of admission.
  4. * Participants must be able to speak and read English.
  1. * Participants diagnosed with dementia and/or cognitive impairments.
  2. * Participants with acute psychiatric complications, such as schizophrenia with acute psychosis, acute mania, or suicidal ideation (which may impact the ability of a participant to consent and actively participate in treatment).
  3. * Participants who are pregnant or lactating at onset of study.
  4. * Participants who cannot read or speak English.

Contacts and Locations

Study Contact

Research Program Coordinator
CONTACT
412-679-9848
thriving@pitt.edu

Principal Investigator

Jacqueline D Wilson, MD
PRINCIPAL_INVESTIGATOR
University of Pennsylvania

Study Locations (Sites)

UPMC Mercy Hospital
Pittsburgh, Pennsylvania, 15203
United States
UPMC Presbyterian-Montefiore Hospital
Pittsburgh, Pennsylvania, 15213
United States
UPMC Shadyside Hospital
Pittsburgh, Pennsylvania, 15232
United States

Collaborators and Investigators

Sponsor: University of Pennsylvania

  • Jacqueline D Wilson, MD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-18
Study Completion Date2028-12

Study Record Updates

Study Start Date2025-02-18
Study Completion Date2028-12

Terms related to this study

Keywords Provided by Researchers

  • Opioid Use Disorder
  • Harm Reduction
  • Peer Support
  • Peer Support Specialists

Additional Relevant MeSH Terms

  • Opioid Use Disorder
  • Harm Reduction