RECRUITING

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

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Conditions

Idiopathic Pulmonary FibrosisHyperpolarized Xenon-129 gas with MRI

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Idiopathic pulmonary fibrosis has a poor prognosis with limited treatment options. The Investigator hypothesize hyperpolarized Xe129-MRI can be performed in patients with IPF and repeated over time which will detect deficiencies related to perfusion in the lung.

Official Title

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

Quick Facts

Study Start:2025-05-01
Study Completion:2027-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06853145

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Able to provide informed consent 18 years of age or greater Clinical diagnosis of IPF
  1. * Continuous oxygen use at home
  2. * Oxygen saturation less than 92% on the day of MRI procedure
  3. * Pregnancy or lactation
  4. * Claustrophobia, inner ear implants, aneurysm or other surgical clips, metal foreign bodies in eye, pacemaker or other contraindication to MR scanning. Subjects with any implanted device that cannot be verified as MRI compliant will be excluded.
  5. * History of congenital cardiac disease, chronic renal failure, or cirrhosis. • Chest circumference greater than that of the xenon MR and/or helium coil. The circumference of the coil is approximately 42 inches.
  6. * Inability to understand simple instructions or to hold still for approximately 10-15 seconds.
  7. * History of respiratory infection within 2 weeks prior to the MR scan
  8. * History of MI, stroke and/or poorly controlled hypertension.

Contacts and Locations

Study Contact

Roselove Asare, MA
CONTACT
4342436074
rnn3b@uvahealth.org
Carol Bampoe, BS
CONTACT

Principal Investigator

John Kim, MD
PRINCIPAL_INVESTIGATOR
University of Virginia

Study Locations (Sites)

Snyder Building 480 Ray C. Hunt Drive
Charlottesville, Virginia, 22908
United States

Collaborators and Investigators

Sponsor: University of Virginia

  • John Kim, MD, PRINCIPAL_INVESTIGATOR, University of Virginia

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-01
Study Completion Date2027-12

Study Record Updates

Study Start Date2025-05-01
Study Completion Date2027-12

Terms related to this study

Keywords Provided by Researchers

  • Hyperpolarized Xenon-129 gas with MRI

Additional Relevant MeSH Terms

  • Idiopathic Pulmonary Fibrosis