RECRUITING

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

Description

Idiopathic pulmonary fibrosis has a poor prognosis with limited treatment options. The Investigator hypothesize hyperpolarized Xe129-MRI can be performed in patients with IPF and repeated over time which will detect deficiencies related to perfusion in the lung.

Conditions

Idiopathic Pulmonary Fibrosis
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Related Conditions:

Idiopathic Pulmonary Fibrosis

Study Overview

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Study Details

Study overview

Idiopathic pulmonary fibrosis has a poor prognosis with limited treatment options. The Investigator hypothesize hyperpolarized Xe129-MRI can be performed in patients with IPF and repeated over time which will detect deficiencies related to perfusion in the lung.

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

Condition
Idiopathic Pulmonary Fibrosis
Intervention / Treatment

-

Contacts and Locations

Charlottesville

Snyder Building 480 Ray C. Hunt Drive, Charlottesville, Virginia, United States, 22908

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Able to provide informed consent 18 years of age or greater Clinical diagnosis of IPF
  • * Continuous oxygen use at home
  • * Oxygen saturation less than 92% on the day of MRI procedure
  • * Pregnancy or lactation
  • * Claustrophobia, inner ear implants, aneurysm or other surgical clips, metal foreign bodies in eye, pacemaker or other contraindication to MR scanning. Subjects with any implanted device that cannot be verified as MRI compliant will be excluded.
  • * History of congenital cardiac disease, chronic renal failure, or cirrhosis. • Chest circumference greater than that of the xenon MR and/or helium coil. The circumference of the coil is approximately 42 inches.
  • * Inability to understand simple instructions or to hold still for approximately 10-15 seconds.
  • * History of respiratory infection within 2 weeks prior to the MR scan
  • * History of MI, stroke and/or poorly controlled hypertension.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Virginia,

John Kim, MD, PRINCIPAL_INVESTIGATOR, University of Virginia

Study Record Dates

2027-12