RECRUITING

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

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Conditions

Patellar Dislocation, RecurrentPatellar DislocationPatellar InstabilityPatellofemoral DislocationPatellofemoral Joint DislocationPatellofemoral DisorderPatellaPatella DislocationRecurrent Patellar InstabilityMPFLMedial Patellofemoral LigamentMedial Patellofemoral Ligament ReconstructionPatellofemoral Instability

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability. The main questions it aims to answer are: * What are the risk factors for recurrent patellar instability after MPFL reconstruction? * What functional outcomes do patients report after MPFL reconstruction? Participants undergoing MPFL reconstruction will answer survey questions about their knee and activity level 1 year and 2 years after surgery.

Official Title

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

Quick Facts

Study Start:2023-01-01
Study Completion:2027-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06883396

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:10 Years to 35 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * 10-35 years old
  2. * Recurrent patellar instability with at least one episode defined as either (1) a dislocated patella requiring reduction in the emergency department or (2) a convincing history for dislocation, associated with full giving way, and the following physical findings: (a) hemarthrosis or effusion, (b) tenderness along the medial retinaculum, and (c) apprehension when laterally directed force was applied to the patella or (3) MRI-documented dislocation with associated bone bruises
  1. * Previous ipsilateral knee surgery
  2. * Obligatory/fixed/habitual patella dislocation or subluxation
  3. * Unloadable inferior or lateral chondral damage on the patella that would require a tibial tubercle transfer for unloading purposes
  4. * Pathologic tibiofemoral instability

Contacts and Locations

Study Contact

Simone Gruber
CONTACT
646-797-8947
grubers@hss.edu
Natalie Pahapill
CONTACT
646-714-6738
pahapilln@hss.edu

Principal Investigator

Beth Shubin Stein, MD
PRINCIPAL_INVESTIGATOR
Hospital for Special Surgery, New York
Shital Parikh, MD
PRINCIPAL_INVESTIGATOR
Children's Hospital Medical Center, Cincinnati

Study Locations (Sites)

Stanford University
Redwood City, California, 94063
United States
University of Florida
Gainesville, Florida, 32607
United States
Midwest Orthopaedics at Rush
Chicago, Illinois, 60612
United States
University of Iowa
Iowa City, Iowa, 52242
United States
Massachusetts General Hospital
Boston, Massachusetts, 02114
United States
Boston Children's Hospital
Boston, Massachusetts, 02115
United States
Mayo Clinic
Rochester, Minnesota, 55905
United States
Mount Sinai
New York, New York, 10012
United States
NYU Langone Health
New York, New York, 10016
United States
Hospital for Special Surgery
New York, New York, 10021
United States
Duke Health
Wake Forest, North Carolina, 27587
United States
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229
United States
Cleveland Clinic
Cleveland, Ohio, 44195
United States
Ohio State University Wexler Medical Center
Dublin, Ohio, 43016
United States
Oregon Health & Science University
Portland, Oregon, 97239
United States
Scottish Rite for Children
Dallas, Texas, 75219
United States

Collaborators and Investigators

Sponsor: Hospital for Special Surgery, New York

  • Beth Shubin Stein, MD, PRINCIPAL_INVESTIGATOR, Hospital for Special Surgery, New York
  • Shital Parikh, MD, PRINCIPAL_INVESTIGATOR, Children's Hospital Medical Center, Cincinnati

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-01
Study Completion Date2027-12

Study Record Updates

Study Start Date2023-01-01
Study Completion Date2027-12

Terms related to this study

Keywords Provided by Researchers

  • Patella
  • Patella Dislocation
  • Patellar Instability
  • Recurrent Patellar Instability
  • MPFL
  • Medial Patellofemoral Ligament
  • Medial Patellofemoral Ligament Reconstruction
  • Patellofemoral Instability

Additional Relevant MeSH Terms

  • Patellar Dislocation, Recurrent
  • Patellar Dislocation
  • Patellar Instability
  • Patellofemoral Dislocation
  • Patellofemoral Joint Dislocation
  • Patellofemoral Disorder