RECRUITING

Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID

Conditions

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is investigating the effects of using an Osteopathic Manipulative Therapy (OMT) treatment protocol that was shown to statistically improve smell in individuals suffering from Long-COVID olfactory (smell) dysfunction in a small single-blinded pilot trial conducted during 2021. The questions this study is trying to answer are: 1. Does this OMT protocol improve other non-smell related Long-COVID symptoms 2. Do 2 OMT treatments improve Long-COVID symptoms more than 1 OMT treatment Participants will: 1. Week 1: Take an digital survey regarding their Long-COVID symptoms undergo Long-COVID OMT treatment or a placebo treatment 2. Week 2: Take an digital survey regarding their Long-COVID symptoms then all will undergo Long-COVID OMT treatment 3. Week 3: Take an digital survey regarding their Long-COVID symptoms 4. Week 8: Take an digital survey regarding their Long-COVID symptoms

Official Title

Osteopathic Manipulative Therapy(OMT) Effects on Post-Acute Sequalae of COVID-19(PASC)

Quick Facts

Study Start:2025-05-01

Study Completion:2025-07-03

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06883513

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* - Individuals must claim they have had a prior positive SARS-CoV-2 test at least 6-weeks before the consenting process to proceed with the study * Individuals must claim they have at least one of the following symptoms greater than 6-weeks post infection that is affecting their daily life(these symptoms correlate with the SBQ™-LC):	* If anyone denies they have any of the above symptoms before consent, they will be excluded from the trial * They will also be excluded from the trial if they have suffered any fractured bones in the last 3 months (this will further decrease risk to the patient as the patient will be moved by the physician during the treatment protocol) * Participants who are enrolled in other Long-COVID trials that have an intervention during their participation in this trial will be excluded. However, if they have a history of enrollment in a long-covid trial that has no interventions during this trial, they will not be excluded based on their history of acquiring experimental treatment.

Inclusion Criteria

Exclusion Criteria

* - Individuals must claim they have had a prior positive SARS-CoV-2 test at least 6-weeks before the consenting process to proceed with the study
* Individuals must claim they have at least one of the following symptoms greater than 6-weeks post infection that is affecting their daily life(these symptoms correlate with the SBQ™-LC):

* If anyone denies they have any of the above symptoms before consent, they will be excluded from the trial
* They will also be excluded from the trial if they have suffered any fractured bones in the last 3 months (this will further decrease risk to the patient as the patient will be moved by the physician during the treatment protocol)
* Participants who are enrolled in other Long-COVID trials that have an intervention during their participation in this trial will be excluded. However, if they have a history of enrollment in a long-covid trial that has no interventions during this trial, they will not be excluded based on their history of acquiring experimental treatment.

Contacts and Locations

Study Contact

Michael E Stenta, DO, Doctor of Osteopathic Medicine

CONTACT

15137289344

michael.stenta@uoflhealth.org

Rebecca Lynn, DO, Doctor of Osteopathic Medicine

CONTACT

1-931-409-6699

rebecca.lynn@uoflhealth.org

Principal Investigator

Darryl Kaelin, MD, Medical Doctorate (US)

PRINCIPAL_INVESTIGATOR

University of Louisville School of Medicine Chair of PM&R Division of the Department of Neurological Surgery

Study Locations (Sites)

University of Louisville Outpatient Care Center

Louisville, Kentucky, 40202

United States

Collaborators and Investigators

Sponsor: University of Louisville

Darryl Kaelin, MD, Medical Doctorate (US), PRINCIPAL_INVESTIGATOR, University of Louisville School of Medicine Chair of PM&R Division of the Department of Neurological Surgery

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-01

Study Completion Date2025-07-03

Study Record Updates

Study Start Date2025-05-01

Study Completion Date2025-07-03

Terms related to this study

Keywords Provided by Researchers

Long-COVID
PASC

Additional Relevant MeSH Terms

Long-COVID
PASC
Long COVID Syndrome