RECRUITING

Maternal Left Lateral Position in Fetal Growth Restriction

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn if maternal left-lateral positioning in pregnancy works to treat fetal growth restriction. This study will also help us learn about the effects of left-lateral positioning on maternal metabolomics, maternal mental health, fetal cardiac function, and delivery outcomes. The main questions it aims to answer are: * Does maternal left-lateral position in a pregnancy with fetal growth restriction improve the baby's growth? * How are maternal metabolomics, delivery outcomes, maternal mental health, and fetal cardiac function impacted by maternal left-lateral position? Researchers will compare the intervention group to pregnancies with fetal growth restriction that receive standard of care (without left-lateral positioning) to see if left-lateral position improves fetal biometry in fetal growth restriction. Participants will: * Practice left-lateral position every day for 4 hours (cumulatively) with 10-mins stretching after every hour of left-lateral position, or continue to receive standard of care * Visit the clinic once after 4 weeks for a follow-up research visit, and at the time of delivery Tracking of the physical activity and adherence to left-lateral position at home in intervention group A will be done through a fitbit (smart watch) given during enrollment. A fitbit will also be given to participants in intervention group B, receiving standard of care, to monitor their physical activity trends at home.

Official Title

Impact of Maternal Left-Lateral Recumbent Positioning in Pregnancies With Fetal Growth Restriction

Quick Facts

Study Start:2025-07-28
Study Completion:2026-12-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06919692

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Pregnant persons between 18 - 65 years of age, with a diagnosis of fetal growth restriction, with an estimated fetal weight less than tenth percentile
  2. * Participants with a singleton pregnancy between 24- and 34-weeks' gestational age
  3. * Participants with fluency in English or Spanish language
  1. * Patients with a known history of deep vein thrombosis, pulmonary embolism, or hypercoagulability disorder
  2. * Patients with a pre-pregnancy BMI greater than 40
  3. * Pregnancy with severe abnormality in umbilical artery Doppler flow, including absent end-diastolic flow (AEDF) and reverse end-diastolic flow (REDF)
  4. * Patients receiving anticoagulation therapy
  5. * Pregnancy with suspected chromosomal anomalies or a multifetal pregnancy
  6. * Patients with an active smoking status during pregnancy

Contacts and Locations

Study Contact

Hannah E Vincent, PhD
CONTACT
7209191019
hannah.vincent@cuanschutz.edu

Principal Investigator

Manesha Putra, MD
PRINCIPAL_INVESTIGATOR
University of Colorado Anschutz, Department of Obstetrics and Gynecology

Study Locations (Sites)

UCHealth Prenatal Diagnosis and Genetics Clinic - Anschutz Medical Campus
Aurora, Colorado, 80045
United States
CU John C. Hobbins Perinatal Center
Denver, Colorado, 80202
United States

Collaborators and Investigators

Sponsor: University of Colorado, Denver

  • Manesha Putra, MD, PRINCIPAL_INVESTIGATOR, University of Colorado Anschutz, Department of Obstetrics and Gynecology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-28
Study Completion Date2026-12-03

Study Record Updates

Study Start Date2025-07-28
Study Completion Date2026-12-03

Terms related to this study

Keywords Provided by Researchers

  • fetal growth restriction
  • left lateral position
  • maternal fetal medicine

Additional Relevant MeSH Terms

  • Fetal Growth Restriction