RECRUITING

Biomarker Role in Assessing Imaging Needs for Mild Cranial Trauma

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to determine whether a blood test can help doctors decide when to use a head CT scan for patients with a mild head injury. Researchers are investigating whether the results from this blood test can aid in making better decisions about patient care and potentially reduce the need for imaging. In this study, researchers will collect blood samples to assess whether this specific blood test can help doctors decide when head imaging is necessary following a head injury. The goal is to determine whether the use of this test can reduce the number of head imaging procedures performed in the emergency department (ED).

Official Title

Biomarker Role in Assessing Imaging Needs for Mild Cranial Trauma

Quick Facts

Study Start:2025-05-31
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06932588

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adults aged 18-65 years old
  2. * Mild TBI, defined as Glasgow Coma Scale (GCS) score 13-15, presenting within 24 hours of injury
  3. * No prior head imaging for the same incident
  4. * Presenting within 24 hours of onset of injury
  1. * Patients with penetrating head injury
  2. * History of known brain abnormality including tumor, cerebrovascular malformation, recent brain surgery (within 6 months), prior head injury (within 6 months)
  3. * Need for emergent surgical intervention for brain or alternate body organ injury
  4. * Need for emergent bedside procedures for hemodynamic or orthopedic stabilization
  5. * Patients deemed at higher risk for decline by the provider prohibit the 15-minute delay in obtaining imaging needed for biomarker testing.

Contacts and Locations

Study Contact

Ali Tfaily, MS
CONTACT
404-616-1000
ali.tfaily@emory.edu

Principal Investigator

Jonathan Grossberg, MD
PRINCIPAL_INVESTIGATOR
Emory University

Study Locations (Sites)

Grady Health System
Atlanta, Georgia, 30303
United States

Collaborators and Investigators

Sponsor: Emory University

  • Jonathan Grossberg, MD, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-31
Study Completion Date2026-06

Study Record Updates

Study Start Date2025-05-31
Study Completion Date2026-06

Terms related to this study

Keywords Provided by Researchers

  • Biomarkers
  • Brain imaging
  • Brain trauma
  • Head CT scan
  • Mild traumatic brain injury (mTBI)

Additional Relevant MeSH Terms

  • Brain Injuries
  • Head Injury