RECRUITING

A Randomized Controlled Trial Comparing the Efficacy of Commercial Weight Management Programs

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study compares the effectiveness of three commercial weight management programs. The primary outcome is absolute and percentage weight change at 12-weeks.

Official Title

The Comparative Effectiveness of Commercial Weight Management Programs in Adults Living With Overweight or Obesity: A Randomized Controlled Trial

Quick Facts

Study Start:2025-05-14

Study Completion:2025-12-31

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06972277

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* 18 years or older * BMI ≥27 kg/m² * Own a bodyweight scale that they can weigh themselves with during the study * Willing and able to comply with study protocol * Capable of providing informed consent * Able to read and write in English * Willing to be randomized * Willing to sign a Non Disclosure Agreement	* Pregnant, lactating, or plans to become pregnant in the next 6 months * Previous bariatric surgery or planned bariatric surgery during the study period * Major surgery within the past 6 months or plans to have surgery during the study period * Participation in the previous 3 months or current participation in a structured behavioral weight loss program * Participation in another structured weight loss program during the study period (i.e., the next 3 months) * Communication needs that would render them unable to understand the study and/or intervention materials * Current or previous history of anorexia or bulimia nervosa * Engagement with vomiting or laxative use within the last 28 days with the aim of controlling their shape or weight * Currently taking anti-obesity medications, planning to take anti-obesity medications in the next 6 months, or previously taken anti-obesity medications in the previous 3 months * Weight loss of ≥ 5 kg (11 lb) in the previous 6 months * Self-reported diagnosis of severe depression, bipolar disorder, substance abuse, or psychosis * Participants who are involved in any other research studies at this time * Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months * Chronic/inflammatory gastrointestinal disorders (irritable bowel syndrome is acceptable) * History of heart problems (e.g., angina, bypass surgery, myocardial infarction, etc.) within previous 6 months * Diagnosis of type 1 or type 2 diabetes * Presence of implanted cardiac defibrillator or pacemaker * History of cancer within past 5 years or current treatment for cancer * Hospitalization for psychiatric disorders during the last 12 months

Inclusion Criteria

Exclusion Criteria

* 18 years or older
* BMI ≥27 kg/m²
* Own a bodyweight scale that they can weigh themselves with during the study
* Willing and able to comply with study protocol
* Capable of providing informed consent
* Able to read and write in English
* Willing to be randomized
* Willing to sign a Non Disclosure Agreement

* Pregnant, lactating, or plans to become pregnant in the next 6 months
* Previous bariatric surgery or planned bariatric surgery during the study period
* Major surgery within the past 6 months or plans to have surgery during the study period
* Participation in the previous 3 months or current participation in a structured behavioral weight loss program
* Participation in another structured weight loss program during the study period (i.e., the next 3 months)
* Communication needs that would render them unable to understand the study and/or intervention materials
* Current or previous history of anorexia or bulimia nervosa
* Engagement with vomiting or laxative use within the last 28 days with the aim of controlling their shape or weight
* Currently taking anti-obesity medications, planning to take anti-obesity medications in the next 6 months, or previously taken anti-obesity medications in the previous 3 months
* Weight loss of ≥ 5 kg (11 lb) in the previous 6 months
* Self-reported diagnosis of severe depression, bipolar disorder, substance abuse, or psychosis
* Participants who are involved in any other research studies at this time
* Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months
* Chronic/inflammatory gastrointestinal disorders (irritable bowel syndrome is acceptable)
* History of heart problems (e.g., angina, bypass surgery, myocardial infarction, etc.) within previous 6 months
* Diagnosis of type 1 or type 2 diabetes
* Presence of implanted cardiac defibrillator or pacemaker
* History of cancer within past 5 years or current treatment for cancer
* Hospitalization for psychiatric disorders during the last 12 months

Contacts and Locations

Study Contact

Michelle I Cardel, PhD, RD

CONTACT

0345 345 1500

michelle.cardel@ww.com

Principal Investigator

Michelle I Cardel, PhD, MS, RD

PRINCIPAL_INVESTIGATOR

WW International Inc

Study Locations (Sites)

WW International, Inc

New York, New York, 10010

United States

Collaborators and Investigators

Sponsor: WW International Inc

Michelle I Cardel, PhD, MS, RD, PRINCIPAL_INVESTIGATOR, WW International Inc

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-14

Study Completion Date2025-12-31

Study Record Updates

Study Start Date2025-05-14

Study Completion Date2025-12-31

Terms related to this study

Additional Relevant MeSH Terms

Obesity and Overweight