COMPLETED

Speech-derived Digital Biomarkers Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal is to assess the accuracy of an application that analyzes voice characteristics to diagnose patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD). The main question is whether the application's diagnosis is the same as the clinician's for MCI and AD patients.

Official Title

Speech-derived Digital Biomarkers for Assessing Mild Cognitive Impairment and Alzheimer's Disease Diagnosis Accuracy

Quick Facts

Study Start:2025-05-19
Study Completion:2026-01-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06994767

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Males and females between the ages of 50 and above
  2. * Willing and capable of participating in all aspects of the study
  3. * Willing and capable of giving informed consent
  4. * Diagnosis of MCI or Alzheimer's by the physician
  5. * For the control group: Without diagnosis of MCI or Alzheimer's or other types of dementia
  6. * Subjects are free of any medical condition(s) that, according to exclusion criteria, might audibly affect voice characteristics
  7. * Subject must be able to speak and read with fluency in the English language.
  1. * All participants below 50 years
  2. * Failure to provide informed consent
  3. * Individuals with the following medical conditions will be excluded:
  4. * Persons with speech characteristics (heavy accents, slurring, stuttering, etc.) that would interfere with voice recording or voice analysis

Contacts and Locations

Principal Investigator

Sakshi Jain, MD
PRINCIPAL_INVESTIGATOR
Hackensack Meridian Health

Study Locations (Sites)

Hackensack University Medical Center
Hackensack, New Jersey, 07601
United States

Collaborators and Investigators

Sponsor: Hackensack Meridian Health

  • Sakshi Jain, MD, PRINCIPAL_INVESTIGATOR, Hackensack Meridian Health

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-19
Study Completion Date2026-01-09

Study Record Updates

Study Start Date2025-05-19
Study Completion Date2026-01-09

Terms related to this study

Keywords Provided by Researchers

  • Vocal biomarkers
  • Mild Cognitive Impairment
  • Alzheimer's Disease
  • Deep machine learning
  • Artificial Intelligence application

Additional Relevant MeSH Terms

  • Mild Cognitive Impairment (MCI)
  • Alzheimer Disease