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Assessment of CSF Shunt Flow and Headaches With a Thermal Measurement Device

Description

This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow over multiple measurements performed by a study subject during headache and non-headache periods.

Conditions

Study Overview

Study Details

Study overview

This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow over multiple measurements performed by a study subject during headache and non-headache periods.

Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device in People With Chronic Headaches

Assessment of CSF Shunt Flow and Headaches With a Thermal Measurement Device

Condition
Hydrocephalus
Intervention / Treatment

-

Contacts and Locations

Chicago

Rhaeos, Inc, Chicago, Illinois, United States, 60642

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Existing ventriculoperitoneal CSF shunt
  • 2. Subject experiencing ongoing headaches including at least 15 headache days per month for the past 3 months
  • 3. Region of intact skin overlying an unambiguously identifiable palpable chronically indwelling ventricular shunt which crosses the clavicle and is appropriate in size for application of the study device
  • 4. Available for remote and in-person follow-up during the 30-day measurement period
  • 5. Signed informed consent by subject or a parent, legal guardian, health care agent, or surrogate decision maker (according to local statutes)
  • 6. Subject or caregiver is able to clearly communicate and document information and shunt symptoms in English
  • 7. Subject is at least 6 years old but not more than 80 years old
  • 1. Presence of more than one distal shunt catheter in the study device measurement region
  • 2. Shunt is not palpable due to depth or depth of shunt where the device will be placed is greater than 4 mm per ultrasound evaluation
  • 3. Presence of an interfering open wound or edema in the study device measurement region
  • 4. Subject-reported history of serious adverse skin reactions to silicone-based adhesives
  • 5. Investigator judges that the subject is likely to be lost to follow-up due to unavailability or clinical outcome being unobtainable
  • 6. Investigator judges that the subject is unlikely to successfully take reliable measurements at home
  • 7. Investigator judges that the subject/subject's caretaker would not be able to successfully place the device without assistance
  • 8. Use of the study device would interfere with standard patient care, or emergency surgery that cannot be delayed, or participation in the study will interfere with, or be detrimental to, administration of optimal healthcare to the subject
  • 9. Prior enrollment in this study
  • 10. Participation in any other investigational procedural, pharmaceutical, and/or device study that may influence the collection of valid data under this study

Ages Eligible for Study

6 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Rhaeos, Inc.,

Study Record Dates

2025-12