RECRUITING

Exploring the Utility of [18F]3F4AP for Demyelination Imaging

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The overall objective is to obtain an assessment of the pharmacokinetics of \[18F\]3F4AP in healthy volunteers and subjects with demyelinating diseases such as mild cognitive impairment (MCI), Alzheimer's Disease (AD), Multiple Sclerosis (MS), Spinal Cord Injury (SCI) and Spinal radiculopathy (SR).

Official Title

Exploring the Utility of [18F]3F4AP for Demyelination Imaging

Quick Facts

Study Start:2025-05-05
Study Completion:2030-05-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06999434

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Shannan Henry
CONTACT
+1 (203) 737-5278
shannan.henry@yale.edu
Kayla Cottiers
CONTACT
203-737-7496
kayla.cottiers@yale.edu

Principal Investigator

Georges El Fakhri, PhD, DABR
PRINCIPAL_INVESTIGATOR
Yale University

Study Locations (Sites)

Yale University PET Center
New Haven, Connecticut, 06510
United States

Collaborators and Investigators

Sponsor: Yale University

  • Georges El Fakhri, PhD, DABR, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-05
Study Completion Date2030-05-05

Study Record Updates

Study Start Date2025-05-05
Study Completion Date2030-05-05

Terms related to this study

Keywords Provided by Researchers

  • 3F4AP
  • Demyelinating Disorders
  • MS
  • SCI
  • AD

Additional Relevant MeSH Terms

  • Demyelinating Disorders
  • MCI
  • Alzheimer's Disease (AD)
  • MS (Multiple Sclerosis)
  • SCI - Spinal Cord Injury
  • Spinal Radiculopathy