RECRUITING

A Study of LY3867070 in Healthy Participants

Description

The purpose of this study is to evaluate how well LY3867070 is tolerated and what side effects may occur in healthy participants. The study drug will be administered orally. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body.

Conditions

Study Overview

Study Details

Study overview

The purpose of this study is to evaluate how well LY3867070 is tolerated and what side effects may occur in healthy participants. The study drug will be administered orally. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body.

A Single- and Multiple-Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of LY3867070 in Healthy Participants

A Study of LY3867070 in Healthy Participants

Condition
Healthy
Intervention / Treatment

-

Contacts and Locations

Anaheim

Anaheim Clinical Trials, LLC, Anaheim, California, United States, 92801

Dallas

Fortrea Clinical Research Unit, Dallas, Texas, United States, 75247

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Are overtly healthy as determined by medical evaluation
  • * Part C of the study includes only Japanese and Chinese participants
  • * Have a body weight greater than or equal to 45 kilogram (kg) and also body mass index 18 to 32 kilogram per square meter (kg/m²) inclusive
  • * Have a history or presence of multiple or severe allergies, anaphylactic reaction to prescription or nonprescription drugs, or history of significant atopy
  • * Have a significant history or current thyroid disease
  • * Have a significant history of or current psychiatric disorders, rheumatologic, cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrine (such as Cushing syndrome and hyperaldosteronism), hematological, or neurological disorders capable of significantly altering the absorption, metabolism, or elimination of drugs; of constituting a risk when taking the investigational medicinal product; or of interfering with the interpretation of data
  • * Have used, or intend to use, prescription or nonprescription medication (including dietary supplements, vitamins, herbal supplements such as St. John's wort, traditional Chinese medicine, or alternative medicines), or any medications known to be strong inhibitors and inducers of the genes CYP1A1, CYP1A2, CYP2B6, CYP3A4 and CYP2C19, within 14 days prior to dosing of any study intervention until end of study assessments are complete
  • * Are smokers (including electronic cigarettes) within 6 months prior to screening and unwilling to refrain from smoking for the duration of the study.
  • * Unwilling to undergo skin biopsies (for Part B only)
  • * Are unwilling to have body hair cut or shaved in cases where hair, in the investigator's opinion, could interfere with noninvasive skin patch

Ages Eligible for Study

18 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Eli Lilly and Company,

Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST), STUDY_DIRECTOR, Eli Lilly and Company

Study Record Dates

2026-08