The researchers are doing this study to find out whether a very low dose of radiation therapy (VLDRT) is an effective treatment for people with follicular lymphoma (FL) or marginal zone lymphoma (MZL) and works as well as the standard dose of radiation therapy. The researchers will see if VLDRT works against cancer in the area that is currently affected by cancer and if the therapy prevents new spots of lymphoma from developing. The researchers will also compare VLDRT with the standard dose of radiation therapy to see if VLDRT causes fewer side effects. Radiation therapy uses beams of intense energy to kill cancer cells. Standard doses of radiation therapy can cause short- and long-term side effects. Researchers think VLDRT may be as effective as standard doses, and, because VLDRT uses less radiation, researchers think VLDRT may cause fewer side effects than standard doses.
The researchers are doing this study to find out whether a very low dose of radiation therapy (VLDRT) is an effective treatment for people with follicular lymphoma (FL) or marginal zone lymphoma (MZL) and works as well as the standard dose of radiation therapy. The researchers will see if VLDRT works against cancer in the area that is currently affected by cancer and if the therapy prevents new spots of lymphoma from developing. The researchers will also compare VLDRT with the standard dose of radiation therapy to see if VLDRT causes fewer side effects. Radiation therapy uses beams of intense energy to kill cancer cells. Standard doses of radiation therapy can cause short- and long-term side effects. Researchers think VLDRT may be as effective as standard doses, and, because VLDRT uses less radiation, researchers think VLDRT may cause fewer side effects than standard doses.
A Study of Reduced Dose Radiation Therapy for People With B-Cell Lymphomas
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Memorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge, New Jersey, United States, 07920
Memorial Sloan Kettering Monmouth (All Protocol Activities), Middletown, New Jersey, United States, 07748
Memorial Sloan Kettering Bergen (All Protocol Activities), Montvale, New Jersey, United States, 07645
Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities), Commack, New York, United States, 11725
Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison, New York, United States, 10604
Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York, United States, 10065
Memorial Sloan Kettering Nassau (All Protocol Activities), Uniondale, New York, United States, 11553
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
No
Memorial Sloan Kettering Cancer Center,
Brandon Imber, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center
2028-06