Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

Eligibility Criteria

• * Subject is 18 -75 years old
• * Subject is considered healthy, with no known illnesses
• * Subject can follow fasting requirements
• * Subject can follow bowel prep instructions
• * Subject can provide informed consent
• * Subject is older than 75 years of age
• * Subject with current dysphagia or any swallowing disorder
• * Subject with any current condition believed to have an increased risk of capsule retention such as gastrointestinal strictures, intestinal tumors, bowel obstruction, incomplete colonoscopies or fistula
• * Subject with a diagnosis of gastroparesis or small bowel or large bowel dysmotility
• * Subject with a history of inflammatory bowel disease (IBD), intestinal Crohn's disease, chronic constipation, or rectal bleeding
• * Subject with clinical evidence of renal disease, including clinically significant laboratory abnormalities of renal function within the past 6 months
• * Subject with chronic usage of nonsteroidal anti-inflammatory drugs (NSAIDs)
• * Subjects with a known contradiction to metoclopramide
• * Subjects with a known contraindication to polyethylene glycol
• * Subject with currently suspected or diagnosed with hematochezia, melena, iron deficiency with or without anemia
• * Subject who has had intestinal surgery in the past
• * Subject with a history of congestive heart failure
• * Subject with Type I or Type II Diabetes
• * Subject has a cardiac pacemaker or other implanted electromedical device.
• * Subject expected to undergo MRI examination within 7 days after ingestion of the capsule.
• * Subject has participated in an investigational drug or device research study within 30 days of enrollment that may interfere with the subject's safety or ability to participate in this study
• * Subject with delayed gastric emptying
• * Subject who is pregnant, suspected pregnant, or is actively breast-feeding.