RECRUITING

Assessment of Circuit Rebreathing During CPAP Therapy

Description

The goal of this research is to better understand how different CPAP mask designs affect airflow and rebreathing of exhaled carbon dioxide (CO₂) during sleep in individuals with obstructive sleep apnea (OSA).

Conditions

Obstructive Sleep Apnea (OSA)
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Related Conditions:

Obstructive Sleep Apnea (OSA)

Study Overview

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Study Details

Study overview

The goal of this research is to better understand how different CPAP mask designs affect airflow and rebreathing of exhaled carbon dioxide (CO₂) during sleep in individuals with obstructive sleep apnea (OSA).

Assessment of Circuit Rebreathing During Continuous Positive Airway Pressure (CPAP) Therapy

Assessment of Circuit Rebreathing During CPAP Therapy

Condition
Obstructive Sleep Apnea (OSA)
Intervention / Treatment

-

Contacts and Locations

Boston

Brigham and Women's Hospital, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Moderate to severe OSA (AHI\>20)
  • * Self-reported CPAP users or have previously used CPAP
  • * Self-reported holding pressure of maximum 13 cmH2O (if known)
  • * Age: 21-70
  • * BMI: 18-40 kg/m2
  • * Self-reported severe mouth-breathing
  • * Requirement for nocturnal supplemental oxygen or other ventilatory support
  • * Severe cardiovascular or pulmonary disease
  • * Any unstable or acute medical condition
  • * Any additional sleep disorder, including insomnia, except for OSA.

Ages Eligible for Study

21 Years to 70 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Brigham and Women's Hospital,

Atqiya Aishah, PhD, PRINCIPAL_INVESTIGATOR, Harvard Medical School & Brigham and Women's Hospital

Study Record Dates

2025-12-01