RECRUITING

Bioavailability of Ration Items Containing Tart Cherry Extract

Description

To determine how consuming food items containing shelf-stored tart cherry impacts your body's ability to absorb and use the compounds within tart cherry.

Conditions

Study Overview

Study Details

Study overview

To determine how consuming food items containing shelf-stored tart cherry impacts your body's ability to absorb and use the compounds within tart cherry.

Bioavailability of Ration Items Containing Tart Cherry Extract

Bioavailability of Ration Items Containing Tart Cherry Extract

Condition
Bioavailability
Intervention / Treatment

-

Contacts and Locations

Natick

USARIEM, Natick, Massachusetts, United States, 01760

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Active duty military personnel and civilians will be invited to participate in the study if they:
  • * Are between the ages of 18 (or 17 for military personnel) and 39.
  • * Are willing to participate in all study procedures and comply with all study instruction.
  • * In good health as determined by OMSO (Office of Medical Support and Oversight).
  • * Supervisor approval for federal civilian employees and non-HRV active-duty military personnel stationed at NSSC
  • * • Unable to understand verbal or written instructions or testing materials in English.
  • * Have a bleeding disorder (e.g., von Willebrand Disease, hemophilia) or are being treated with medication that will impair blood clotting (for example, coumadin)
  • * Have a history of GI-related conditions that may impact macronutrient absorption (e.g., Crohn's disease, ulcerative colitis, Celiac's disease or gluten sensitivity, bariatric surgery or gastroparesis, short bowel, inflammatory bowel disease, etc...);
  • * Any use of antibiotics or antifungal, except topical antibiotics/antifungals within 3 months of study participation.
  • * Colonoscopy within 3 months of study participation.
  • * Regular (i.e., weekly or more frequent) use of over-the-counter medications (including antacids, laxatives, stool softeners, and antidiarrheals) unless approved by OMSO and study PI.
  • * Are habitually taking nonsteroidal anti-inflammatory drugs (e.g., Advil, aspirin), corticosteroids (e.g., prednisone) or immunosuppressants (e.g. Humira);
  • * Have an allergy or aversion (extreme dislike) to any of the test foods(e.g., cherry flavored beverages or bar). Allergy symptoms may include anaphylaxis, hives or eczema, tingling/itching in the mouth, dizziness or fainting, diarrhea, nausea or vomiting, swelling of the lips, face, tongue and throat).
  • * Have donated blood within the past 8 weeks of the first test session or plan to donate blood during the study.
  • * Are not willing to abstain from tobacco products and vigorous exercise for at least 24 hours" before each trial and consume a low-polyphenol diet two days prior to each test session and on the day of the test session.

Ages Eligible for Study

17 Years to 39 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

United States Army Research Institute of Environmental Medicine,

Tracey Smith, PhD, PRINCIPAL_INVESTIGATOR, United States Army Research Institute of Environmental Medicine

Study Record Dates

2025-12-31