RECRUITING

Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

Description

The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.

Conditions

Anterior Uveitis (AU)Birdshot ChorioretinitisBehcet DiseaseHerpes Simplex VirusJuvenile Idiopathic Arthritis (JIA)Spondyloarthritis (SA)SarcoidosisPosterior Vitreous Detachment
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Related Conditions:

Anterior Uveitis (AU)Birdshot ChorioretinitisBehcet DiseaseHerpes Simplex VirusJuvenile Idiopathic Arthritis (JIA)Spondyloarthritis (SA)SarcoidosisPosterior Vitreous Detachment

Study Overview

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Study Details

Study overview

The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.

Objective Grading of Intraocular Inflammation in Uveitis Using Optical Coherence Tomography

Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

Condition
Anterior Uveitis (AU)
Intervention / Treatment

-

Contacts and Locations

Portland

Casey Eye Institute - Oregon Health & Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, JIA arthritis associated chronic anterior uveitis, HSV anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade.
  • 2. Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD).
  • 3. Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery.
  • 1. Inability to give informed consent.
  • 2. Inability to maintain stable fixation for OCT imaging.
  • 3. Inability to commit to required visits to complete the study.
  • 4. Pregnancy and breastfeeding.

Ages Eligible for Study

5 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Oregon Health and Science University,

Yan Li, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2026-12