Clinical Trial Results for Heartburn

6 Clinical Trials for Heartburn

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RECRUITING
A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring
Description

The main objective of the study is to compare the maternal, fetal, and infant outcomes of pregnant women who are exposed to vonoprazan during pregnancy with outcomes of an internal comparison cohort of pregnant women who are unexposed to vonoprazan during pregnancy but who may be exposed to other products for the treatment of conditions for which vonoprazan may be prescribed.

RECRUITING
A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Description

Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.

RECRUITING
Domperidone in Treating Patients With Gastrointestinal Disorders
Description

This phase III trial studies how well domperidone works in treating patients with gastrointestinal disorders. Domperidone may help control chronic gastrointestinal disorders and their symptoms, such as pain, bloating, and nausea and vomiting, by stimulating contraction of the stomach to increase its ability to empty itself of food.

RECRUITING
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
Description

The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms

Conditions
RECRUITING
Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD
Description

This study will be conducted as a multi-center, randomized, double-blind, placebo-controlled trial to evaluate the effect of MHS-1031 on heartburn-free days in subjects with GERD-related heartburn symptoms.

RECRUITING
Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life
Description

To assess short and long term outcomes after minimally invasive esophagectomy compared to open esophagectomy. To compare both standard outcome measures as well as patient derived outcome measures, in particular, quality of life (QOL). To look at the applicability of this QOL instrument to this patient group.