Treatment Trials

4 Clinical Trials for Various Conditions

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      Quality of Life in Patients With Congenital Afibrinogenemia
      Description

      The aim of this observational study is to evaluate the quality of life in patients with congenital afibrinogenemia using the Haemo-QoL SF for kids and the Haem-A-QoL for adult patients.

      Conditions

      Afibrinogenemia, Congenital

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      Pharmacokinetics, Efficacy, and Safety of Human Plasma-Derived Fibrinogen (FIB Grifols) in Participants With Congenital Afibrinogenemia
      Description

      The main objective of this study was to evaluate the pharmacokinetics (PK), efficacy, and safety of human plasma-derived fibrinogen concentrate FIB Grifols after a single-dose 70 milligrams/kilogram (mg/kg) body weight administration.

      Conditions

      Congenital Afibrinogenemia

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      Human Fibrinogen Concentrate in Pediatric Cardiac Surgery
      Description

      The goal of the study is to determine whether the use of Human Fibrinogen Concentrate (RiaSTAP) will decrease blood loss and the need for component blood therapy in neonates and infants undergoing cardiopulmonary bypass.

      Conditions

      Hypofibrinogenemia, Afibrinogenemia, Bleeding Disorders

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      Pharmacokinetic, Efficacy, and Safety Study of Octafibrin Compared to Haemocomplettan/Riastap
      Description

      The purpose of this study is to investigate pharmacokinetic properties, surrogate efficacy and safety of Octafibrin compared to Haemocomplettan® P/RiaSTAPTM in patients with congenital fibrinogen deficiency

      Conditions

      Congenital Fibrinogen Deficiency, Afibrinogenemia

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