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Showing 1-2 of 2 trials for Fgfr-gene-alterations
Recruiting

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

Tennessee

Phase 2 Study of TYRA-300 in FGFR3 Altered Low Grade, Intermediate Risk NMIBC

Low-grade NMIBCFGFR Gene AmplificationFGFR Gene AlterationsFGFR3 Gene Alteration
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Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

California · Los Angeles, CA

A Phase 1 study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamic (PD), and preliminary antitumor activity of TYRA-430 in cancers with FGF/FGFR pathway aberrations, including locally advanced/metastatic hepatocellular carcinoma and other advanced solid tumors.

Metastatic Hepatocellular CarcinomaSolid TumorsSolid Tumor, AdultFGFR Gene Amplification
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