Treatment Trials

2 Clinical Trials for Various Conditions

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COMPLETED
Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation
Description

In this study, the investigators test 2 dose levels of thiotepa (5 mg/kg and 10 mg/kg) added to the backbone of targeted reduced dose IV busulfan, fludarabine and rabbit anti-thymocyte globulin (rATG) to determine the minimum effective dose required for reliable engraftment for subjects undergoing hematopoietic stem cell transplantation for non-malignant disease.

RECRUITING
Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms
Description

This cross-sectional prevalence assessment study involves a single blood draw in specific patient populations to assess for enzymatic and genomic evidence for acquired pyruvate kinase deficiency.