Treatment Trials

6 Clinical Trials for Various Conditions

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RECRUITING
Pathogenetic Basis of Aortopathy and Aortic Valve Disease
Description

The main purpose of this study is to define the complex genetic and pathogenic basis of thoracic aortic aneurysm (TAA) and other forms of aortopathy and/or aortic valve disease by identifying novel disease-causing genes and by identifying important genetic modifiers for aortic and aortic valve disease severity.

ACTIVE_NOT_RECRUITING
Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)
Description

The ASCEND post-market clinical follow-up study is undertaken to evaluate safety and clinical performance of the On-X Ascending Aortic Prosthesis (AAP) used in surgical aortic valve replacement.

ENROLLING_BY_INVITATION
Endovascular Treatment of Thoracic Aortic Disease
Description

The purpose of this study is to assess the role endovascular therapy to treat aortic disease involving the ascending aorta, the aortic arch, and the visceral segment of the aorta (or thoracoabdominal aorta)

TERMINATED
Dosing of Amicar and Measure of Fibrinolysis by TEG During Cardiac Surgery
Description

This study hopes to determine the optimal antifibrinolytic dosing to decrease bleeding and blood transfusion after cardiac surgery without increasing adverse events

Conditions
RECRUITING
Valved Graft PMCF Study
Description

Multicenter, global, prospective, non-randomized, interventional, post-market trial. All subjects enrolled will receive an Abbott Valved Graft device.

COMPLETED
Progel Vascular Sealant
Description

This study is being conducted to evaluate the safety and effectiveness of the Progel Vascular Sealant for use in vascular reconstructions to achieve adjunctive hemostasis by mechanically sealing areas of leakage.