Treatment Trials

2 Clinical Trials for Various Conditions

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COMPLETED
Atypical Lesions of the Breast: Close Observation Versus Excision (ALCOVE)
Description

This study is designed to look at whether it is feasible to observe women with atypical ductal hyperplasia (ADH) of the breast, or whether surgical excision is necessary.

ACTIVE_NOT_RECRUITING
Ruxolitinib for Premalignant Breast Disease
Description

This study is evaluating how ruxolitinib affects premalignant breast cells. One half of the study participants will receive ruxolitinib for approximately 15 days, and the other half will receive a placebo (sugar pill) for approximately 15 days. Once study participants have completed their ruxolitinib or placebo, participants will undergo surgery to remove the premalignant breast tissue.