Treatment Trials

2 Clinical Trials for Various Conditions

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      ACTIVE_NOT_RECRUITING
      A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene
      Description

      This study evaluates the safety, tolerability and efficacy of QR-1123 injection in the eye (intravitreal; IVT) injections (one eye/unilateral) in subjects receiving a single dose or repeat doses. Single injections will be assessed in an open label way, and repeat injections will be assessed in a double-masked, randomized, sham-controlled fashion.

      Conditions
      Autosomal Dominant Retinitis PigmentosaEye DiseasesEye Diseases, HereditaryRetinal DystrophiesRetinal DiseaseRetinitisVision TunnelVision Disorders
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      TERMINATED
      Observational Natural History Study of Autosomal Dominant Retinitis Pigmentosa (adRP)
      Description

      The purpose of this study is to gain an understanding of how adRP progresses over time in patients with misfolded rod opsin mutations.

      Conditions
      Retinitis Pigmentosa
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