Treatment Trials

2 Clinical Trials for Various Conditions

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      RECRUITING
      A Study of Sovilnesib in Subjects with Ovarian Cancer
      Description

      This is a randomized, phase 1b study to assess the safety, tolerability, pharmacokinetics (PK), and efficacy of sovilnesib at different dose levels to establish the Recommended Phase 2 Dose (RP2D) of sovilnesib in subjects with high grade serous ovarian cancer (HGSOC).

      Conditions
      High Grade Serous Adenocarcinoma of OvaryFallopian Tube CancerPrimary Peritoneal CarcinomaChromosomal Instability
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      RECRUITING
      A Phase I/II Study of VLS-1488 in Subjects with Advanced Cancer
      Description

      This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers.

      Conditions
      Advanced Solid TumorHigh Grade Serous Adenocarcinoma of OvarySquamous Non-small-cell Lung CancerTriple Negative Breast CancerGastric AdenocarcinomaColorectal AdenocarcinomaEsophageal Squamous Cell CarcinomaEsophageal AdenocarcinomaGastroesophageal Junction AdenocarcinomaTransitional Cell Carcinoma of BladderHead and Neck Squamous Cell CarcinomaOvarian CarcinosarcomaUterine CarcinosarcomaUterine Serous CarcinomaEndometrium CancerChromosomal Instability
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