Treatment Trials

6 Clinical Trials for Various Conditions

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RECRUITING
Fecal Microbiota Transplant for Patients With Chronic Pouchitis
Description

The purpose of this research study is to assess the safety and efficacy of fecal microbiota transplant (FMT) in the treatment of chronic pouchitis.

WITHDRAWN
Treating Chronic Pouchitis With a Low FODMAP Diet
Description

We aim to determine whether low FODMAP diet in patients with chronic pouchitis will improve symptoms and pouch inflammation.

Conditions
TERMINATED
Tofacitinib For Treatment Of Chronic Pouchitis
Description

A phase 2 pilot study to evaluate the effectiveness of tofacitinib in subjects with chronic pouchitis

COMPLETED
A Study to Evaluate the Efficacy and Safety of Vedolizumab in the Treatment of Chronic Pouchitis
Description

The purpose of this study is to compare the efficacy of vedolizumab intravenous (IV) and placebo in terms of the percentage of participants with chronic or recurrent pouchitis achieving clinically relevant remission.

Conditions
NOT_YET_RECRUITING
Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch
Description

The goal of this clinical trial is to learn if mirikizumab works to treat pouch disorders in adults. The main questions it aims to answer are: Does mirikizumab reduce symptoms of pouch disorders Participants will: Take mirikizumab every 4 weeks for one year Visit the clinic once every month for two months and at the end of the study Keep a diary of their symptoms

WITHDRAWN
Stem Cells for the Treatment of Pouchitis
Description

The purpose of this study is to determine the safety and feasibility of using allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat people with medically refractory Pouchitis.