Treatment Trials

3 Clinical Trials for Various Conditions

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      RECRUITING
      fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
      Description

      Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).

      Conditions
      Pain, PostoperativePain, ChronicPain, AcuteSurgical InjurySurgical WoundCornea InjuryCorneaKeratoconus
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      COMPLETED
      Use of Cross-linked Donor Corneas as Carriers for the Boston Keratoprosthesis
      Description

      The purpose of the pilot study is to test the efficacy and safety of riboflavin/Ultraviolet A (UVA) cross-linked human donor corneas as carriers for the Boston Keratoprosthesis (Boston KPro) in patients with higher risk for corneal melting (keratolysis).

      Conditions
      Chemical InjuriesUnspecified Complication of Corneal TransplantAutoimmune DiseasesOcular Cicatricial PemphigoidStevens Johnson SyndromeLupus Erythematosus, SystemicRheumatoid ArthritisOther Autoimmune Diseases
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      COMPLETED
      Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft
      Description

      The main aim of the study is to determine the safety and feasibility of a cultivated autologous limbal epithelial cell (CALEC) transplantation in the treatment of limbal stem cell deficiency.

      Conditions
      Limbal Stem Cell Deficiency
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